How molecular escorts help prevent cancer

The anti-tumor protein p53 can decide on the life or death of a cell: If it detects damage in the cell’s genome, the protein pushes the cell to suicide. New research conducted at Technical University of Munich (TUM) shows that this inborn cancer prevention only works when special proteins, known as chaperones, allow it to take place. A cancer therapy […]

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Estrogen receptors might hold key in obesity prevention

Despite countless fad diets, both obesity and metabolic diseases continue to plague communities across the U.S. Now, researchers from the University of Missouri believe that the clue to treatment might be related to estrogen—for both men and women. In two separate studies, Vicki Vieira Potter and Jaume Padilla, researchers in the Department of Nutrition and Exercise Physiology, have found that […]

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First anticoagulant approved for preventing VTE recurrence in children

(HealthDay)—Fragmin (dalteparin sodium) injection has been granted the first approval for subcutaneous use in preventing recurrence of symptomatic venous thromboembolism (VTE) in children aged 1 month or older, the U.S. Food and Drug Administration announced. Fragmin has been approved for use in adults since 1994. Approval in children was based on a trial of 38 pediatric patients with symptomatic deep […]

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Study paves way for better treatment of lingering concussion symptoms

A La Trobe University study has lifted the lid on the debilitating effects of persistent post-concussion symptoms (PCS) felt by many—10% of concussion-sufferers—after a knock to the head. The results of the study, released in Neuroscience journal, show that significant levels of fatigue and poorer brain function can persist for months, or even years, following concussion. Renowned concussion expert Professor […]

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IL-1 inhibitors may reduce radiation-induced vascular damage

Radiation therapy against cancer can increase the risk of cardiovascular disease much later in life, as the radiation causes chronic inflammation of the exposed blood vessels. In a new study published in the European Heart Journal, researchers from Karolinska Institutet in Sweden have shown that these inflammations can be treated with IL-1 inhibitors. Damage to healthy tissue is one of […]

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Biochemical compound responsible for blood pressure drop in sepsis is discovered

A study conducted by an international group of researchers has overturned the understanding of life-threatening inflammatory diseases such as sepsis, pointing to a biochemical agent that may be involved in the rapid decline in blood pressure that occurs in the advanced stage of sepsis and usually causes the patient’s death. This discovery could pave the way for novel therapeutic approaches. […]

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Dietary fats entering the brain may explain link between obesity and depression

Obesity and depression have long been linked, with previous clinical studies finding an association between these two conditions. However, until now, the mechanisms of how obesity affects depression and vice versa have not been fully understood. Now, in a new study led by the University of Glasgow in collaboration with the Gladstone Institutes, and published today in Translational Psychiatry, scientists […]

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