Scientists reveal novel oncogenic driver gene in human gastrointestinal stromal tumors

Sarcomas—cancers that arise from transformed mesenchymal cells (a type of connective tissue)—are quite deadly. Gastrointestinal stromal tumors (GISTs) are the most common human sarcoma and are initiated by activating mutations in the KIT receptor tyrosine kinase. Micro-GISTs are a smaller variation of clinical GISTs and are found in one-third of the general population without clinical symptoms. Although the micro-GISTs and […]

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Researchers find risk factors for unemployment with multiple sclerosis vary by age

A recent study by Kessler Foundation researchers explored numerous factors that contribute to the high unemployment rate among individuals of different ages with multiple sclerosis (MS). This is the first investigation to consider age within the context of disease- and person-specific factors affecting employment in MS. The article, “Unemployment in multiple sclerosis across the ages: How factors of unemployment differ […]

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New approach to shutting down breast cancer recurrence shows promise in mice

A new approach to treat advanced breast cancer shuts down the growth of cells that become resistant to standard hormone therapy, according to Duke Cancer Institute animal studies. The research, which is likely to be tested in clinical trials within the year, identified and targeted vulnerabilities that appear in nearly all estrogen-positive breast cancers that develop resistance to current treatments. […]

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Common brain disorders accelerate brain aging

Common brain disorders seem to be associated with accelerated aging of the brain, according to a new international study using machine learning models to analyse structural brain MRI data from more than 45,000 individuals. The researchers discovered that people with memory disorders, multiple sclerosis (MS) and schizophrenia, among other conditions, have an older-looking brain than it really is; however, there […]

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Retired? Hardly: At 99, this pioneering heart doctor still leading the way

At 99 years old, most people are not engaging in complex research funded by the National Institutes of Health (NIH). Dr. Jeremiah Stamler is no ordinary person. The author and co-author of hundreds of peer-reviewed studies and books, Stamler’s cutting-edge research into the cardiovascular health impact of lifestyle factors like diet, smoking, diabetes, cholesterol and blood pressure has been cited […]

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Humans’ ‘inner salamander’ capacity could regrow cartilage

Humans have the ability to regrow cartilage, a new study has found. In a way similar to how salamanders and other creatures can regrow lost limbs, humans have the capacity to repair and regenerate cartilage in their joints, researchers at Duke Health discovered. “We believe that an understanding of this ‘salamander-like’ regenerative capacity in humans, and the critically missing components […]

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Nothing clinically ‘wrong’ with obsessive gamers, new study finds

Research by Oxford University, carried out in partnership with Cardiff University, and published today in Clinical Psychological Science, has found little evidence to suggest an unhealthy passion for gaming amongst adolescents, often referred to as “gaming addiction,” requires clinical intervention by medical professionals. Based on data from over 1,000 adolescents and their caregivers, the study suggests those engaged in dysfunctional […]

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Recalling good memories together

Recalling positive memories can help you feel better about yourself. Charlotte van Schie is aiming to use this fact to help people with a borderline personality disorder become stronger. She has written about her research for Human Brain Mapping, and at the LIBC open day on 11 October she gave a “flash talk” titled “Coloured memories in the brain.” Positive […]

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