Sleep disturbances linked to increased dementia risk

Researchers at Karolinska Institutet in Sweden report that sleep disturbances in midlife or in late life are associated with a higher risk for developing dementia in old age. The results are published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. The results show that in midlife, when participants were in their 40s or 50s, insomnia was associated with […]

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Cold fronts may increase stroke mortality

A study performed by Brazilian researchers and published in the International Journal of Biometeorology showed that falling temperatures may be accompanied by rising numbers of deaths from stroke, especially among people over 65. The authors also found that in the case of older people, the incidence of stroke associated with colder weather was higher among women. With the support from […]

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Low/no calorie soft drinks linked to improved outcomes in advanced colon cancer patients

Drinking artificially-sweetened beverages is associated with a significantly lower risk of colon cancer recurrence and cancer death, a team of investigators led by a Yale Cancer Center scientist has found. The study was published today in the journal PLOS ONE. “Artificially sweetened drinks have a checkered reputation in the public because of purported health risks that have never really been […]

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The cause of prostate cancer progression to the incurable stage has likely been uncovered

Researchers at the University of Oulu in Finland have discovered novel genes and mechanisms that can explain how a genomic variant in a single nucleotide polymorphism (SNP) rs11672691 influences prostate cancer aggressiveness. Their findings also suggest ways to improve risk stratification and clinical treatment for advanced prostate cancer. The study is published in the journal Cell. Three billion base pairs […]

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Switching to certain antidiabetic drugs linked to increased risk of major complications

For people with type 2 diabetes, switching to sulfonylurea drugs to control blood sugar levels is associated with an increased risk of complications compared with staying on the drug metformin, finds a study in The BMJ today. As such, the researchers say that continuing metformin when introducing sulfonylureas is safer than switching. Metformin is a “first-line” therapy (the first drug […]

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New guidelines to diagnose, manage rare endocrine disorders

International guidelines have been published for the first time to help doctors around the globe diagnose and manage patients with a very rare set of endocrine diseases known as pseudohypoparathyroidism and its related disorders, including Albright hereditary osteodystrophy (AHO). It’s the realization of a long-term goal for physician-scientist Dr. Emily Germain-Lee of the UConn School of Medicine and Connecticut Children’s […]

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Study reveals long-term effectiveness of therapy for common cause of kidney failure

New research provides support for the long-term efficacy of a drug used to treat in patients with autosomal dominant polycystic kidney disease (ADPKD), a common cause of kidney failure. The findings appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). The hormone vasopressin promotes the progression of ADPKD, the fourth leading cause of […]

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