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Imagine—or perhaps you don’t have to—that you’re at work and feeling very tired. You’re nearing the deadline on an important project, and you’ve stayed late at the office every day for weeks. Perhaps because you’re feeling so fatigued, when you submit an expense report for a recent lunch, you may round up just a smidge. Now imagine you are the […]
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The breast cancer drug lapatinib which is designed to shrink tumours can sometimes cause them to grow in the lab, according to a new study published in eLife. By understanding the molecular basis of this phenomenon, scientists hope that their findings will lead to safer treatment decision-making and drug design in the future. Lapatinib is used in combination with other […]
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Wearable fitness trackers, such as Fitbits, that measure steps taken per day may be a useful tool to evaluate and help treat cancer patients, researchers at UT Southwestern’s Simmons Cancer Center have shown. A pilot study of older cancer patients found that they were willing to wear physical activity monitors (PAMs) for 10 weeks or more and used them correctly. […]
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Inhaled medications play an important role in treating chronic obstructive pulmonary disease, or COPD, and it is imperative that the inhaler device be used properly to effectively treat the disease. However, in a recently released study in the Journal of the COPD Foundation, researchers from Baylor College of Medicine and other institutions found that healthcare providers and patients prioritize medication […]
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Doctors could be a step closer to finding the most effective way to treat cancer with a double whammy of a virus combined with boosting the natural immune system, according to a pioneering study by researchers at The University of Texas Health Science Center at Houston (UTHealth) and The Ohio State University. “The findings of this research are very exciting […]
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From burning your palm on a hot pan handle to memorizing the name of a new acquaintance, “anytime you experience something, your neurons are active,” says Kelsey Tyssowski, a graduate student in genetics at Harvard Medical School. Different experiences stimulate different patterns of activity in brain cells. Researchers want to track these activity patterns to better understand how the brain […]
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Scientists from the University of Cambridge have identified a potential therapeutic target in the devastating genetic disease Hutchinson-Gilford Progeria Syndrome (HGPS), which is characterised by premature ageing. In a paper published today in Nature Communications, scientists provide preclinical data showing that chemical inhibition or genetic deregulation of the enzyme N-acetyltransferase 10 (NAT10) leads to significant health and lifespan gains in […]
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University of Colorado Cancer Center researchers recently completed the largest-ever study of thyroid cancer genetics, mining the data of 583 patient samples of advanced differentiated thyroid cancer and 196 anaplastic thyroid cancers. In addition to identification of specific genes that may drive these cancers and thus provide attractive targets for treatment, the researchers found that in several samples of advanced […]
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The ability to perform simple daily tasks can make a big difference in people’s lives, especially for those with spinal cord injuries. A UCLA-led team of scientists reports that six people with severe spinal cord injuries—three of them completely paralyzed—have regained use of their hands and fingers for the first time in years after undergoing a nonsurgical, noninvasive spinal stimulation […]
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A new study showing significantly improved survival rates for patients with stage IV Wilms tumors with lung metastases was recently published in the Journal of Clinical Oncology. The outcomes of the study, “Treatment of Stage IV Favorable Histology Wilms Tumor With Lung Metastases: A Report From the Children’s Oncology Group AREN0533 Study”, will be a game-changer in treating Wilms tumor […]
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