Healthy blood stem cells have as many DNA mutations as leukemic cells

Researchers from the Princess Máxima Center for Pediatric Oncology have shown that the number of mutations in healthy and leukemic blood stem cells does not differ. Rather, the location of DNA mutations is relevant. Using the mutation patterns in hematopoietic stem and progenitor cells (HSPCs), the team was able to trace the developmental lineage tree of the cells. Van Boxtel, […]

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This Is the One Thing This Woman Wishes Someone Would Have Told Her Before Losing 336 Pounds

When Brittany May started her weight-loss journey over two years ago, she knew she would have loose skin when she reached her goal. Now she’s 336 pounds lighter—but she wasn’t prepared for just how heavy that extra skin would really be and how much pain it would cause her. “Nobody talked about the pain loose skin can cause and the discomfort and […]

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Encouraging more health workers to have flu jab needs new approach that connects on an emotional level

Persuading more health workers to have the flu jab to protect themselves and their patients cannot be done through facts and statistics alone, new research by a leading behavioural scientist from Kingston University has revealed. Instead it demands a new approach that connects with people emotionally to sustain immunisation rates at effective levels. Nearly one third of nurses, GPs and […]

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Cells in ‘little brain’ have distinctive metabolic needs

Cells’ metabolic needs are not uniform across the brain, researchers have learned. “Knocking out” an enzyme that regulates mitochondria, cells’ miniature power plants, specifically blocks the development of the mouse cerebellum more than the rest of the brain. The results are scheduled for publication in Science Advances. “This finding will be tremendously helpful in understanding the molecular mechanisms underlying developmental […]

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Quality of life after spinal cord injury—What functional abilities have the greatest impact?

Independence in mobility is the single most important factor affecting quality of life in patients with traumatic spinal cord injury (TSCI), reports a study in the American Journal of Physical Medicine & Rehabilitation, the official journal of the Association of Academic Physiatrists. Based on validated clinical questionnaires, the study by Julien Goulet, MD, and colleagues of Hôpital du Sacré-Coeur de […]

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Prince Harry & Meghan Markle Won't Have Custody of Their Future Children — Um, What?!

Sometimes, real life is stranger than fiction. For example, this surprising news from our friends in England: Apparently, when Prince Harry and Meghan Markle, who are now the Duke and Duchess of Sussex, have children, those kids will technically not belong to them. What? You see, in an interview with News.com.au, royal expert Marlene Koenig explained what is commonly referred […]

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