Telemedicine provides accurate diagnosis of rare cause of blindness in preemies

Accurately detecting a rare, but devastating cause of blindness in premature babies can be done as effectively with telemedicine as with traditional, in-person eye exams, a study published in JAMA Ophthalmology suggests. This is believed to be the first study to directly compare the two approaches. The finding could enable more blindness-preventing treatment for infants born in rural and other […]

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New recommendations for endoscopic eradication therapy in Barrett’s esophagus

The latest issue of GIE: Gastrointestinal Endoscopy, the official journal of the American Society for Gastrointestinal Endoscopy (ASGE), includes a new society guideline on use of endoscopic eradication therapy Barrett’s esophagus. A new guideline by the ASGE Standards of Practice Committee offers evidence-based recommendations and clinical guidelines addressing key issues related to Endoscopic Eradication Therapy (EET) in the management of […]

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Massive single-cell survey of kidney cell types reveals new paths to disease

The kidney is a highly complex organ – far beyond a simple filter. Its function requires intricate interactions between many highly specialized cell types to extract waste, balances body fluids, form urine, regulate blood pressure, and secrete hormones. New research from a team in the Perelman School of Medicine at the University of Pennsylvania shines a light on specific cell […]

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New rapid-fire method using pathology images, tumor data may help guide cancer therapies

By combining data on pathology images of 13 types of cancer and correlating that with clinical and genomic data, a Stony Brook University-led team of researchers are able to identify tumor-infiltrating lymphocytes (TILs), called TIL maps, which will enable cancer specialists to generate tumor-immune information from routinely gathered pathology slides. Published in Cell Reports , the paper details how TIL […]

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Early intervention may minimise later lung problems

A major study has found that controlling asthma through appropriate monitoring and medication is among several variables that can affect whether someone develops chronic obstructive pulmonary disease (COPD) in later life. The University of Melbourne-led study, published in The Lancet Respiratory Medicine, was the world’s first to characterise lung function trajectories that could lead to COPD in a large general […]

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Reducing severity of PTSD symptoms long-term holds significant public-health and economic implications

Both civilians and military veterans with post-traumatic stress disorder (PTSD) reap long-term benefits from psychotherapies used for short-term treatment, according to a new study from Case Western Reserve University. The findings suggest effective and lasting approaches for symptoms of PTSD—a debilitating and typically chronic disorder that rarely diminishes spontaneously and is associated with significant distress, impairment and considerable economic costs. […]

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Using mathematical models to determine the best chemotherapy schedules

Can mathematical models predict how can cancer cells respond to varied chemotherapy schedules? In other words, should cancers associated with fast-growing tumors, like brain cancer, be treated using a low drug dose administered continuously, as opposed to a high drug dose given periodically? Professor Paul Newton and Ph.D. recipient Jeffrey West have developed a tool that can predict the best […]

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Attention deficit disorders could stem from impaired brain coordination

Researchers from Case Western Reserve University School of Medicine and colleagues have discovered how two brain regions work together to maintain attention, and how discordance between the regions could lead to attention deficit disorders, including schizophrenia, bipolar disorder, and major depression. People with attention deficits have difficulty focusing and often display compulsive behavior. The new study suggests these symptoms could […]

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