Gene-edited disease monkeys cloned in China

The first cohort of five gene-edited monkey clones made from fibroblasts of a monkey with disease phenotypes were born recently at the Institute of Neuroscience (ION) of the Chinese Academy of Sciences (CAS) in Shanghai. The expression of BMAL1, a core circadian regulatory transcription factor, was knocked out in the donor monkey using CRISPR/Cas9-mediated gene editing at the embryo stage, […]

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Innovative diagnostic test could revolutionise cervical cancer screening

Coinciding with Cervical Cancer Prevention Week, researchers at St George’s are working on a field study to fine-tune an exciting new method of human papilloma virus testing that could revolutionise care for women in low and middle income countries. The research team have partnered with molecular diagnostics firm QuantuMDx for the study, using the company’s Q-POC platform and its human […]

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Researchers discover new type of blood vessel in the bones of mice

A team of researchers affiliated with multiple institutions across Germany has discovered a new type of blood vessel in mouse bones. In their paper published in the journal Nature Metabolism, the group describes making sample mouse bones transparent, as well as their microscopic properties. Christopher Ritchlin and Iannis Adamopoulos with the University of Rochester and the University of California, respectively, […]

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People with boring jobs tend to design dull jobs for their colleagues

Managers and professional employees who have boring and dull jobs themselves are more likely to design demotivating, disengaging, low-skill and repetitive jobs for others, new research led by Curtin University has found. The research, published in the Journal of Applied Psychology, examined how individuals, including managers and professionals, make decisions that influence other people’s quality of work. Lead author ARC […]

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Liver transplants double for alcohol-related liver disease

The proportion of U.S. liver transplants for alcohol-associated liver disease (ALD) has doubled in the last 15 years, in part due to broader acceptance of waiving the mandated period of sobriety before transplants for this population, according to a study by researchers at UC San Francisco. However, the study showed ongoing regional geographic variations in liver transplant rates for ALD […]

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As work gets more ambiguous, younger generations may be less equipped for it

We work in a world of increasing ambiguity. Over the past few decades technological change and globalisation have fundamentally changed the nature of the “average” job. There is greater competition and higher expectations. We face more situations, projects, tasks or objectives that are new, different, unclear or inexact. To investigate whether Australian workers are equipped to handle this growing ambiguity […]

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The metabolism of the intestinal microbiota in the first year of life

A research team with the participation of the Institute for Integrative Systems Biology (I2SysBio) of the University of Valencia, together with FISABIO and CIBERESP, has carried out the first metatranscriptomic study of the gut microbiota of babies, which extends knowledge of the metabolism of intestinal bacterial communities during the first year of life with an unprecedented level of detail. This […]

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