Marmosets as the canary in the coal mine for Zika

New research shows small, New World monkeys called marmosets may be an important animal model for emerging viruses with the potential for harmful effects on fetuses. Establishing animal models for emerging diseases, like Zika, is necessary for the development of vaccines, therapies and diagnostics. Results of a study published in the journal Scientific Reports showed pregnant marmosets inoculated with the […]

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Antibody ‘cocktail’ can prevent Zika infection but is not effective for treatment of fetuses

A “cocktail” of monoclonal antibodies that can prevent Zika virus (ZIKV) infection in primates was not effective for treatment of fetuses, according to a new collaborative study led by a University of Miami Miller School of Medicine research team. “We observed that ZIKV isolated from pregnant women in Rio de Janeiro also causes fetal infection in pregnant macaques. Unfortunately, we […]

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Researchers advise long-term monitoring of infants infected with Zika after birth

A collaborative research team led by Ann Chahroudi, MD, PhD, of Emory University is recommending long-term clinical monitoring for infants infected with Zika virus early after birth. The recommendation is based on the team’s research results showing for the first time that postnatal Zika virus infection of rhesus macaque infants results in persistent abnormalities in brain structure and function as […]

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