Blood vessels instruct brain development

Function and homeostasis of the brain relies on communication between its complex network of cells. Consequently, development of the different groups of cells in the brain needs to be coordinated in time and space. The group of Amparo Acker-Palmer (Buchmann Institute of Molecular Life Sciences and the Institute of Cell Biology and Neuroscience, Goethe University) reported in the last issue […]

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Lymphatic vessels unexpectedly promote the spread of cancer metastases

Lymphatic vessels actively contribute to the spread of cancer metastases from various organs. This unexpected realisation is the result of a joint study by researchers from ETH Zurich and the University Hospital Zurich as part of the research initiative Skintegrity. Together with medical experts from the University Hospital Zurich, researchers from ETH Zurich have discovered a new mechanism by which […]

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Small vessels with big impact on cardiovascular disease

Cardiovascular diseases are commonly associated with large vessel atherosclerosis. However, accumulating evidence demonstrates disturbances in the small arteries that control tissue perfusion. In particular, under specific conditions such as hypertension, aging, diabetes and obesity, these vessels undergo alteration in size and function, a process known as small artery remodelling. Such changes limit the capacity of these vessels to deliver oxygen […]

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Tobacco aside, e-cigarette flavorings may harm blood vessels

Flavor additives used in electronic cigarettes and related tobacco products could impair blood vessel function and may be an early indicator of heart damage, according to new laboratory research in Arteriosclerosis, Thrombosis and Vascular Biology, an American Heart Association journal. The health effects of “combustible” tobacco products including traditional cigarettes and hookah are well-established, but the potential dangers of e-cigarettes […]

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Novel antioxidant makes old blood vessels seem young again

Older adults who take a novel antioxidant that specifically targets cellular powerhouses, or mitochondria, see age-related vascular changes reverse by the equivalent of 15 to 20 years within six weeks, according to new University of Colorado Boulder research. The study, published this week in the American Heart Association journal Hypertension, adds to a growing body of evidence suggesting pharmaceutical-grade nutritional […]

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Molecule that dilates blood vessels hints at new way to treat heart disease

Americans die of heart or cardiovascular disease at an alarming rate. In fact, heart attacks, strokes and related diseases will kill an estimated 610,000 Americans this year alone. Some medications help, but to better tackle this problem, researchers need to know exactly how the heart and blood vessels stay healthy in the first place. Now, scientists at The Scripps Research […]

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