Downward-facing mouse: Stretching reduces tumor growth in mouse model of breast cancer

Many cancer patients seek out gentle, movement-based stretching techniques such as yoga, tai chi and qigong, but does stretching have an effect on cancer? While many animal studies have attempted to quantify the effects of exercise on the disease, results have been mixed. Furthermore, studies in animals involve levels of vigorous exercise that can be difficult for cancer patients. Investigators […]

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Genetic counseling and testing proposed for patients with the brain tumor medulloblastoma

Researchers have identified six genes that predispose carriers to develop the brain tumor medulloblastoma and have used the discovery to craft genetic counseling and screening guidelines. The study appears today in the journal The Lancet Oncology. St. Jude Children’s Research Hospital, Hopp Children’s Cancer Center at the NCT Heidelberg (KiTZ), Germany, and The Hospital for Sick Children, Toronto, led the […]

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132-pound tumor removed from woman’s abdomen

Doctors at a Connecticut hospital say they removed a 132-pound tumor from a woman’s abdomen, and she is expected to recover fully. The ovarian tumor was diagnosed after the 38-year-old woman reported rapid weight gain of about 10 pounds per week over a two-month period. The doctors at Danbury Hospital announced Thursday that the five-hour surgery was completed successfully after […]

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Noninvasive brain tumor biopsy on the horizon

Taking a biopsy of a brain tumor is a complicated and invasive surgical process, but a team of researchers at Washington University in St. Louis is developing a way that allows them to detect tumor biomarkers through a simple blood test. Hong Chen, a biomedical engineer, and Eric C. Leuthardt, MD, a neurosurgeon, led a team of engineers, physicians and […]

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Study shows a new approach to treating patients with stage IV Wilms tumor

A new study showing significantly improved survival rates for patients with stage IV Wilms tumors with lung metastases was recently published in the Journal of Clinical Oncology. The outcomes of the study, “Treatment of Stage IV Favorable Histology Wilms Tumor With Lung Metastases: A Report From the Children’s Oncology Group AREN0533 Study”, will be a game-changer in treating Wilms tumor […]

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Protein can slow intestinal tumor growth

A new mechanism for regulating stem cells in the intestine of fruit flies has been discovered by researchers at Stockholm University. In addition, it was discovered that a certain protein can slow the growth of tumours in intestinal tissue. A better understanding of these mechanisms can teach us more about how diseases in human intestines occur, as well as contribute […]

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New paper suggests that tumor cells may develop resistance to potential Ras inhibitors

Researchers have long sought a treatment aimed specifically at the Ras family of genes, the most common oncogenes and those that initiate many of the most lethal tumours. However, the results of a hypothetical treatment may be far less positive than speculated, according to a manuscript published in Genes & Development by the Genomic Instability Group at the Spanish National […]

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Machine learning finds tumor gene variants and sensitivity to drugs in The Cancer Genome Atlas

Matching unique genetic information from cancer patients’ tumors with treatment options – an emerging area of precision medicine efforts – often fails to identify all patients who may respond to certain therapies. Other molecular information from patients may reveal these so-called “hidden responders,” according to a Penn Medicine study in Cell Reports this week. The findings are published alongside several […]

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Index of tumor cells opens a new perspective to prevent cancer progression

Researchers from the School of Medicine in Ribeirão Preto (FMRP), at the University of São Paulo (USP), in collaboration with international groups, have developed indices that provide information about the prognosis of cancers, aid in the choice of the most appropriate therapy and identify potential targets for the development of new drugs. Their paper, titled “Machine Learning Identity Stemness Features […]

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New rapid-fire method using pathology images, tumor data may help guide cancer therapies

By combining data on pathology images of 13 types of cancer and correlating that with clinical and genomic data, a Stony Brook University-led team of researchers are able to identify tumor-infiltrating lymphocytes (TILs), called TIL maps, which will enable cancer specialists to generate tumor-immune information from routinely gathered pathology slides. Published in Cell Reports , the paper details how TIL […]

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