tuberculosis Archives - Family Medicine News

How an AI solution can design new tuberculosis drug regimens

22.11.2019 Health Problems

With a shortage of new tuberculosis drugs in the pipeline, a software tool from the University of Michigan can predict how current drugs—including unlikely candidates—can be combined in new ways to create more effective treatments. “This could replace our traditional trial-and-error system for drug development that is comparatively slow and expensive,” said Sriram Chandrasekaran, U-M assistant professor of biomedical engineering, […]

Countries pledge billions to fight tuberculosis worldwide

27.09.2018 Health Problems

The World Health Organization says governments have agreed to contribute $13 billion a year by 2022 to prevent and treat tuberculosis, a communicable disease that claimed at least 1.3 million lives last year. The agency said Wednesday that countries at a high-level meeting on the sidelines of the U.N. General Assembly committed an additional $2 billion annually for research into […]

Scientists develop new drug treatment for tuberculosis

11.09.2018 Health Problems

Scientists at The University of Manchester have developed the first non-antibiotic drug to successfully treat tuberculosis in animals. The team hope the compound -developed after 10 years of painstaking research will be trialled on humans within three to four years. The drug- which works by targeting Mycobacterium tuberculosis’ defences rather than the bacteria itself—can also take out its increasingly commonly […]

Higher doses of rifampin appear more effective in fighting tuberculosis without increasing risk of adverse events

29.06.2018 Health Problems

Higher daily doses of rifampin, a cornerstone of tuberculosis treatment, killed more TB bacteria in sputum cultures, and the higher doses did so without increasing the adverse effects of treatment, according to a randomized controlled trial published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine. In “Efficacy and Safety of High-Dose Rifampin in Pulmonary […]

Blood signature could improve early tuberculosis diagnosis

19.06.2018 Health Problems

A gene signature in the bloodstream could reveal whether someone is going to develop active tuberculosis (TB) disease months before symptoms begin. Such a signature has now been developed by a team led by the Francis Crick Institute and University of Leicester, in collaboration with BIOASTER and bioMerieux in France and the University of Cape Town in South Africa. The […]