Researchers turn to Yelp reviews to learn how patients with addiction rate their treatment

As the opioid crisis has worsened, addiction treatment programs have proliferated—but there’s no standardized way to rate those programs, researchers at the University of Pennsylvania note in a new study. So they turned to Yelp. The popular online review site is best-known for its restaurant ratings. But it’s also become a clearinghouse for people to rate just about anything—including addiction […]

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CRISPR-Cas9 datasets analysis leads to largest genetic screen resource for cancer research

A comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 genetic screens in 725 cancer models, across 25 different cancer types. Scientists at the Wellcome Sanger Institute and the Broad Institute of MIT and Harvard compared the consistency of the two datasets, independently verifying the methodology and findings. The […]

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Type 1 diabetes: A new starting point to delay autoimmune response

Regulatory T cells (Tregs) prevent excessive immune reactions in healthy people. In the development of autoimmune type 1 diabetes, this protection is not sufficiently effective. Researchers at Helmholtz Zentrum München and LMU Munich have now deciphered a mechanism that impairs Treg differentiation and stability. In the study, when researchers inhibited the molecule that triggers this mechanism, an increased number of […]

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Disruption of glycine receptors to study embryonic development and brain function

Glycine receptors are among the most widely distributed inhibitory receptors in the central nervous system and have important roles in a variety of physiological processes. Researchers from Max Planck Florida Institute for Neuroscience (MPFI), University of Toyama, Yamagata University, Cairo University, RIKEN Center for Integrative Medical Sciences and Setsunan University collaborated to study glycine receptors, particularly glycine receptor alpha-4 (Glra4), […]

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Jennifer Garner's Son Samuel, 7, Sweetly Promises to 'Always' Be Her Date

Does it get any sweeter than this? Jennifer Garner has a date for her life in her son, Samuel. “I asked my 7-year-old son if he would always be my date to @disneyonice,” the actress, 47, captioned a Monday, December 16, Instagram video. “’Always, Mom. Even when I’m a grown-up.’ #spoileralert #tinkwasrescued.” https://www.instagram.com/p/B6J93pvpYrx/ I asked my seven year old son […]

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Rapid tissue donation program offers feasible approach to improve research

Precision medicine with targeted therapies has led to improved treatment options and patient outcomes. These approaches were developed by studying tumors grown in laboratories and patient samples obtained before and during their treatment. However, there is often a limited supply of patient samples to adequately study, and the samples that exist do not always tell the complete genetic story of […]

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Brad Pitt Didn't Try to See Maddox While Overseas: There Is 'No Contact'

Father-son feud! Brad Pitt didn’t visit his 18-year-old son, Maddox, at Yonsei University earlier this month while the actor was traveling overseas. “Brad didn’t try to see Maddox,” a source exclusively reveals in the new issue of Us Weekly. “There’s been no contact between them.” That being said, the Ad Astra star, 55, hasn’t given up hope on reconciling with his and […]

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