Get fit to cut your diabetes risk during pregnancy

(HealthDay)—If she’s fit, a woman is less likely to develop diabetes during pregnancy, a new study contends. Researchers who followed 1,300 U.S. women found that high levels of fitness before pregnancy were tied to a 21 percent lower risk of gestational diabetes. These findings show that women should think about getting into shape before conceiving, according to the University of […]

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Previous stroke tied to higher risks in aortic valve replacement

(HealthDay)—For patients undergoing surgical aortic valve replacement (SAVR), previous stroke is a risk factor for recurrent ischemic stroke and major adverse cardiovascular events (MACE), according to a study published online April 25 in JAMA Cardiology. Charlotte Andreasen, M.D., from the Copenhagen University Hospital Herlev and Gentofte in Denmark, and colleagues conducted a cohort study involving 14,030 patients with aortic valve […]

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Contemporary update to PROGRESS-CTO International Registry shows successful outcomes

A significant update to the PROGRESS-CTO (PROspective Global Registry for the Study of Chronic Total Occlusion Intervention) International Registry was presented today as late-breaking clinical science at Society for Cardiovascular Angiography and Interventions (SCAI) Scientific Sessions 2018. The study includes results of Chronic Total Occlusion Percutaneous Intervention (CTO PCI) for more than 3,000 patients across 20 centers in the United […]

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Researchers map the potential spread of yellow fever virus to cities around the world

The deadly yellow fever virus has the potential to spread into cities around the world where it previously hasn’t been seen, according to a new study led by St. Michael’s Hospital. Researchers led by Dr. Kamran Khan of St. Michael’s have mapped the worldwide pathways through which yellow fever virus could spread by analyzing global patterns of airline travellers, the […]

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PARP-1 may be key to effectiveness of PARP inhibitors, and now researchers can image it

Penn Medicine researchers have used CRISPR/Cas9 gene editing technology to isolate a key genetic feature that could cause resistance to PARP inhibitors in patients with ovarian cancer—and they’ve also proven they have a way to see that feature using PET imaging. The team found PARP inhibitors—a type of targeted therapy that kills cancer cells with mutations in their DNA repair […]

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Noninvasive spinal stimulation method enables paralyzed people to regain use of hands, study finds

The ability to perform simple daily tasks can make a big difference in people’s lives, especially for those with spinal cord injuries. A UCLA-led team of scientists reports that six people with severe spinal cord injuries—three of them completely paralyzed—have regained use of their hands and fingers for the first time in years after undergoing a nonsurgical, noninvasive spinal stimulation […]

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Common class of drugs linked to dementia even when taken 20 years before diagnosis

The largest and most detailed study of the long-term impact of anticholinergic drugs, a class of drugs commonly prescribed in the United States and United Kingdom as antidepressants and incontinence medications, has found that their use is associated with increased risk of dementia, even when taken 20 years before diagnosis of cognitive impairment. An international research team from the US, […]

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Study shows a new approach to treating patients with stage IV Wilms tumor

A new study showing significantly improved survival rates for patients with stage IV Wilms tumors with lung metastases was recently published in the Journal of Clinical Oncology. The outcomes of the study, “Treatment of Stage IV Favorable Histology Wilms Tumor With Lung Metastases: A Report From the Children’s Oncology Group AREN0533 Study”, will be a game-changer in treating Wilms tumor […]

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