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Chronic lymphocytic leukemia patient goes into remission thanks to single CAR T cell

30.05.2018 Health Problems

The doctors who have spent years studying the case call it “a series of fortunate events.” What began as a remarkable response to chimeric antigen receptor (CAR) T cell therapy is now providing evidence about the human genome and immune response that could help turn gene therapy non-responders into responders. Researchers at the University of Pennsylvania’s Abramson Cancer Center say […]

Six tips to spot cancer ‘fake news’

30.05.2018 Health Problems

Cancer is a popular topic for the media, as people care and worry about it in equal measure. News reports help people find out what researchers are working on, and how charitable donations are being spent. They also helps generate interest in the amazing science going on. But perhaps most of all, health stories and clinical trial results have a […]

Impaired energy production may explain why brain is susceptible to age-related diseases

29.05.2018 Health Problems

Defective energy production in old neurons might explain why our brains are so prone to age-related diseases. Salk researchers used a new method to discover that cells from older individuals had impaired mitochondria—the power stations of cells—and reduced energy production. A better understanding of the effects of aging on mitochondria could reveal more about the link between mitochondrial dysfunction and […]

Two teams independently come up with a way to avert CRS in CAR T-cell therapies

29.05.2018 Health Problems

Two teams of researchers, one working in the U.S., the other in Italy, have come up with new ways to avert cytokine release syndrome (CRS) in leukemia patients who undergo CAR T-cell therapies. In the first, the researchers working at the Sloan Kettering Cancer Center in New York developed a mouse model to replicate the conditions under which CRS develops. […]

Report identifies characteristics of microorganisms most likely to cause a global pandemic

29.05.2018 Health Problems

Infectious disease preparedness work focuses predominantly on an historical list of pathogens derived from biological warfare agents, political considerations, and recent outbreaks. That fails to account for the most serious agents not currently known or without historical precedent, write scholars from the Johns Hopkins Center for Health Security in a new report on the traits of microorganisms with high pandemic […]

Biochemist, physicist team to see antibacterial TCS deform mitochondria

28.05.2018 Health Problems

Grocery shopping can be an illuminating chore for a toxicologist. Julie Gosse, a University of Maine associate professor of molecular and biomedical sciences, has scanned the supermarket aisles for products that contain triclosan (TCS), a synthetic antibacterial agent. Since the ’90s, TCS has been in a slew of consumer products, including facial cleansers, toothpaste, mouthwash and hand sanitizers. For years, […]

Five ways to protect your eye health

26.05.2018 Health Problems

(HealthDay)—Your risk of vision problems increases with age, but there are things you can do to protect your sight, eye doctors say. By age 65, one in three Americans will have a vision-impairing eye disease. But early treatment of many of these conditions can slow or halt vision loss, or even restore normal vision, according to the American Academy of […]

The brain’s frontal lobe could be involved in chronic pain, according to research

25.05.2018 Health Problems

A University of Toronto scientist has discovered the brain’s frontal lobe is involved in pain transmission to the spine. If his findings in animals bear out in people, the discovery could lead to a new class of non-addictive painkillers. For 20 years, Min Zhuo, a professor of physiology in the Faculty of Medicine, has been intrigued by invisible pain, in particular chronic […]

New blood test to detect liver damage in under an hour

25.05.2018 Health Problems

A quick and robust blood test that can detect liver damage before symptoms appear has been designed and verified using clinical samples by a team from UCL and University of Massachusetts. The researchers say the test could address a huge need for early detection of liver disease as it distinguishes between samples taken from healthy individuals and those with varying […]

Changes to specific MicroRNA involved in development of Lou Gehrig’s disease

23.05.2018 Health Problems

A new Tel Aviv University study identifies a previously unknown mechanism involved in the development of Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS). The research focuses on a specific microRNA whose levels were found to decrease as a result of ALS-causing muscular mutations. The study highlights, for the first time, the importance of toxic muscle-secreting molecules in the pathology […]

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