GI bleeding research points to need for updated Medicare policies

Penn Medicine researchers are calling for greater precision in Medicare performance reporting for patients with gastrointestinal (GI) bleeding following an evaluation of patients with the condition. GI bleeding results in significant complications, deaths, and healthcare costs in the United States. This year, a new Medicare inpatient reporting program was implemented to assess patients with GI bleeding to better address quality […]

Continue reading »

Biomaterial particles educate immune system to accept transplanted islets

By instructing key immune system cells to accept transplanted insulin-producing islets, researchers have opened a potentially new pathway for treating type 1 diabetes. If the approach is ultimately successful in humans, it could allow type 1 diabetes to be treated without the long-term complications of immune system suppression. The technique, reported June 4 in the journal Nature Materials, uses synthetic […]

Continue reading »

Researchers discover how colon cancer mutates to escape the immune system

A UCLA-led study has found how colon cancer alters its genes during development in order to avoid detection by the immune system, creating a specific genetic imprint in the process. This ability of cancer to change its genes—a process called immunoediting—had never been described in colon cancer before, and the new understanding could help researchers develop new immunotherapies that target […]

Continue reading »

New study points to a potential ‘Achilles heel’ in brain cancer

Scientists at Virginia Commonwealth University believe they have uncovered an “Achilles heel” of glioblastoma multiforme (GBM), the most common and deadly form of brain cancer. Their study published this week in the Proceedings of the National Academy of Sciences details how a mechanism that protects glioma stem cells can potentially be exploited to develop new and more effective treatments for […]

Continue reading »

Scientists discover a new way to control blood pressure

New, improved ways to fight hypertension and low blood pressure may be in the offing, thanks to a discovery of how blood pressure is controlled. National University of Singapore researchers have found a new means of controlling blood pressure that involves the protein galectin-1, present in blood vessels and various other tissues. The researchers showed that galectin-1 reduces the activity […]

Continue reading »

Neuroscientists discover roles of gene linked to Alzheimer’s

People with a gene variant called APOE4 have a higher risk of developing late-onset Alzheimer’s disease: APOE4 is three times more common among Alzheimer’s patients than it is among the general population. However, little is known about why this version of the APOE gene, which is normally involved in metabolism and transport of fatty molecules such as cholesterol, confers higher […]

Continue reading »

Metabolically ‘healthy’ obesity still linked to higher risk of cardiovascular disease

Women who are obese and who have been metabolically healthy for decades are still at higher risk of developing cardiovascular disease compared to metabolically healthy women of normal weight, according to an observational study that followed over 90000 American women for up to 30 years, published in The Lancet Diabetes & Endocrinology journal. The findings indicate that obesity is a […]

Continue reading »

Elevated HbA1c usually leads to prompt Tx start, intensification

(HealthDay)—Most patients are newly initiated on antidiabetic therapy or have antidiabetic therapy intensified within six months of hemoglobin A1c (HbA1c) elevation, according to a study published online May 24 in Diabetes Care. Lauren G. Gilstrap, M.D., from Harvard Medical School in Boston, and colleagues used data from 2008 to 2015 commercial claims linked with laboratory and pharmacy data to create […]

Continue reading »
1 44 45 46 47 48 60