First in-depth profile of CAR T-cell signals suggests how to improve immunotherapy

Health Problems

CAR T-cell therapy, which reprograms immune cells to fight cancer, has shown great promise in people with some blood cancers who have not responded to other treatments. But until now, the underlying biological pathways enabling anti-cancer responses have not been thoroughly examined. Understanding these pathways is important for designing future generations of CAR T-cell therapies, including reducing side effects, preventing […]

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Research shows it’s possible to reverse damage caused by aging cells

Health Problems

What’s the secret to aging well? University of Minnesota Medical School researchers have answered it- on a cellular level. Aging starts in our cells, and those aging cells can hasten cellular senescence, leading to tissue dysfunction and related health impacts. New research involving University of Minnesota Medical School faculty Paul D. Robbins and Laura J. Niedernhofer, recently published in Nature […]

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Using DeepMind’s neural network learning system to diagnose eye diseases

Health Problems

Three institutions working together have applied DeepMind’s neural network learning system to the task of discovering and diagnosing eye diseases. Moorfields Eye Hospital has been working with Google’s DeepMind Health subsidiary and University College London in the effort, and have documented their progress in a paper published in Nature Medicine. As the researchers note, eye doctors currently use a machine […]

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From sexting to breaking up, texting can bring us close or drive us apart, studies find

Health Problems

Texting has the power to both help and hinder our relationships, whether we’re tapping our fingers to stay in touch or using our smartphones to avoid difficult situations, according to research on texting and sexting presented at the annual convention of the American Psychological Association. For instance, couples with similar texting habits tend to be happier and more fulfilled, according […]

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Discovery could lead to better treatment for leukemia

Health Problems

Previous research has revealed that patients with acute myeloid leukemia who also have a particular mutation in a gene called NPM1 have a higher rate of remission with chemotherapy. About one-third of leukemia patients possess this favorable mutation, but until now, how it helps improve outcomes has remained unknown. Scientists from the University of Illinois at Chicago report on how […]

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Dietary carbohydrates could lead to osteoarthritis, new study finds

Health Problems

Do your knees ache? According to new findings from the Oklahoma Medical Research Foundation, your diet could be a culprit. In a study led by OMRF scientist Tim Griffin, Ph.D., researchers found that the carbohydrate composition of diets increased the risk of osteoarthritis in laboratory mice—even when the animals didn’t differ in weight. “We know increased body fat elevates risk, […]

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Scientists tie specific brain circuit to sociability in mice

Health Problems

Social behavior in mouse models of autism spectrum disorder normalized when investigators triggered the release of a specific signaling substance, serotonin, in a single part of the animals’ brains, according to a study from the Stanford University School of Medicine. “This points to a previously understudied brain mechanism that contributes to an inability to derive pleasure from social interactions,” said […]

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