Suppression of DKK3 protein thwarts pancreatic tumor progression and prolongs survival

Researchers at The University of Texas MD Anderson Cancer Center have shed new light on why pancreatic tumors are so resistant to therapy. The answer may lie in treating a protein found in the scar-type tissue called stroma which often surrounds the tumors. The tumor-associated stroma is comprised mostly of pancreatic stellate cells (PSCs) and its density and possibly the […]

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Study links BAP1 protein to tumor suppression in kidney, eye, bile duct and mesothelioma cancers

Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a form of cell death called ferroptosis, opening up a potential new area of therapy research. Findings from the study, led by Boyi Gan, Ph.D., associate […]

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