Small vessels with big impact on cardiovascular disease

Cardiovascular diseases are commonly associated with large vessel atherosclerosis. However, accumulating evidence demonstrates disturbances in the small arteries that control tissue perfusion. In particular, under specific conditions such as hypertension, aging, diabetes and obesity, these vessels undergo alteration in size and function, a process known as small artery remodelling. Such changes limit the capacity of these vessels to deliver oxygen […]

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High protein diet associated with small increased heart failure risk in middle-aged men

For middle-aged men, eating higher amounts of protein was associated with a slightly elevated risk for heart failure than those who ate less protein, according to new research in Circulation: Heart Failure, an American Heart Association journal. Despite the popularity of high protein diets, there is little research about how diets high in protein might impact men’s heart failure risk. […]

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How a small molecule halts the spread of a toxic protein associated with Alzheimer’s progression

Alzheimer’s disease destroys brain cells in part by promoting the formation of insoluble clumps that contain a protein called tau. Not only are these “tau aggregates” toxic for the cells that harbor them, but they also invade and destroy neighboring brain cells, or neurons, which speeds the cognitive decline associated with the Alzheimer’s. For those reasons, Alzheimer’s researchers have been […]

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