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The diagnosis is one that a family never wants to hear: Your father has Alzheimer’s disease. Your mother has stroke-related dementia. A recently released study, included in a special supplement to the Journal of Gerontology, indicates that dementia’s impact might be compressing a bit. That is, people might be developing dementia later and living with it for a shorter period […]
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BLU-667, a next-generation inhibitor that selectively targets the oncogenic receptor tyrosine kinase RET, was well tolerated and had broad clinical benefit in patients with advanced cancer that had progressed on previous therapies including multikinase inhibitor therapy. Proof-of-concept data will be presented from an ongoing phase I clinical trial at the AACR Annual Meeting 2018, April 14-18, in Chicago. “RET-altered cancers […]
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In a study published online today in Science Translational Medicine, Albert Einstein College of Medicine researchers report that an experimental peptide (small protein) drug shows promise against the often-lethal cancer acute myeloid leukemia (AML) and describe how the drug works at the molecular level. The findings have led to a Phase I/II clinical trial for patients with advanced AML and […]
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Differing perceptions of risk among child welfare social workers is leading to inconsistent outcomes for children in need, a University of Otago-led study reveals. Lead author, Senior Lecturer in Social Work Dr. Emily Keddell, says children in similar circumstances can receive variable interventions or decisions from child welfare services because of social workers’ different perceptions of risk, safety and future […]
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A mother’s “basic instinct” to grab her wandering offspring and return them to the nest depends on a specific set of brain cell signals, a new study in mice finds. Reporting in the journal Neuron online April 4, NYU School of Medicine scientists traced the roots of this behavior to brain cells that make the signaling chemical dopamine, release of […]
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