Studies show promise of immunotherapy combinations, including CAR T

As immunotherapies continue to make up a larger share of new cancer drugs, researchers are looking for the most effective ways to use these cutting edge treatments in combination with each or with other pre-existing options. New studies from the Abramson Cancer Center of the University of Pennsylvania are providing fresh clues on potentially effective combinations with CAR T therapy […]

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Study may show how chronic early-life stress raises PTSD vulnerability

A collaboration between investigators at Massachusetts General Hospital and Khyber Medical University in Pakistan may have discovered how chronic stress experienced early in life increases vulnerability to post-traumatic stress disorder (PTSD) later in life. In their report published in Translational Psychiatry the researchers describe finding that chronic stress induces a persistent increase in the hormone ghrelin, both in a rat […]

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Sleepless nights show ties to Alzheimer’s risk

Even one night of lost sleep may cause the brain to fill with protein chunks that have long been linked to the development of Alzheimer’s disease, a new study warns. People deprived of sleep for one night experience an immediate and significant increase in beta amyloid, a substance that clumps together between neurons to form plaques that hamper the brain’s […]

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Nicotine-imbibing teenage rats show an increased risk for drinking alcohol as adults

Rats that were dosed with nicotine during their adolescence grew up to drink more alcohol than those that weren’t exposed to nicotine or were only exposed to it during adulthood, found researchers from the Perelman School of Medicine at the University of Pennsylvania. Exposure to nicotine at a young age changes the neuronal circuitry in the brain’s reward pathways, according […]

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Red or blue in the face? Study says conservatives show less emotion

If playing in a high-stakes poker game, it may be better to face opponents on the liberal side of the political spectrum. That’s because new research from the University of Nebraska–Lincoln has demonstrated a correlation between political ideology and facial expressivity: Conservatives have better poker faces, while liberals may allow more tells. Previous research has shown that people can identify […]

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