Heart-on-a-chip mimics drug response seen in humans

Researchers from TARA Biosystems, Inc. and GlaxoSmithKline (GSK) today published data demonstrating that TARA’s engineered heart-on-a-chip system replicated drug responses found in adult humans. The findings, published in the journal Toxicological Sciences, show TARA’s 3-D-cardiac tissue platform can predict how human hearts will respond to a wide range of drugs, something that has been a challenge in pre-clinical models until […]

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No evidence of legacy effect seen for intensive glucose lowering

(HealthDay)—There seems to be no evidence of a legacy effect or mortality benefit for intensive glucose control among military veterans with type 2 diabetes, according to a study published in the June 6 issue of the New England Journal of Medicine. Peter D. Reaven, M.D., from the Phoenix Veterans Affairs Health Care System, and colleagues report 15-year follow-up for intensive […]

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Remission of schizophrenia seen with amisulpride, clozapine

(HealthDay)—Remission can be achieved for most cases of schizophrenia and schizophreniform disorder with amisulpride and clozapine, according to a study published online Aug. 13 in the The Lancet Psychiatry. René S. Kahn, M.D., from Brain Center Rudolf Magnus in Utrecht, Netherlands, and colleagues recruited 481 participants from 27 centers in 14 European countries and Israel. Patients aged 18 to 40 […]

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