Study reveals large regional variations on future trends of diabetes dependent on if obesity rates are tackled

New research presented at this year’s annual meeting of the European Association for the Study of Diabetes (EASD) in Berlin looks into the rising prevalence of both obesity and type 2 diabetes (T2D) around the world and estimates the population that will likely be affected by both conditions over the coming decades. The research conducted by University College London, Steno […]

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Study reveals long-term effectiveness of therapy for common cause of kidney failure

New research provides support for the long-term efficacy of a drug used to treat in patients with autosomal dominant polycystic kidney disease (ADPKD), a common cause of kidney failure. The findings appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). The hormone vasopressin promotes the progression of ADPKD, the fourth leading cause of […]

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Brain tingles—first study of its kind reveals physiological benefits of ASMR

Autonomous sensory meridian response (ASMR) – the relaxing ‘brain tingles’ experienced by some people in response to specific triggers, such as whispering, tapping and slow hand movements – may have benefits for both mental and physical health, according to new research. In the first study of its kind into the physiological underpinnings of ASMR, researchers from the University of Sheffield […]

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New lab study reveals how breast cancer drug can accelerate cancer cell growth

The breast cancer drug lapatinib which is designed to shrink tumours can sometimes cause them to grow in the lab, according to a new study published in eLife. By understanding the molecular basis of this phenomenon, scientists hope that their findings will lead to safer treatment decision-making and drug design in the future. Lapatinib is used in combination with other […]

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Study reveals large differences in drug prescriptions for newborns between NICUs

Little is known concerning how extensively drugs are prescribed to newborns in different neonatal intensive care units (NICUs). A new British Journal of Clinical Pharmacology study of nearly 1,500 newborns admitted during 12 months to four different NICUs in The Netherlands found that drug use varies widely. Cardiovascular and nervous system drugs were most often prescribed off-label in relation to […]

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New liquid biopsy-based cancer model reveals data on deadly lung cancer

Small cell lung cancer (SCLC) accounts for 14 percent of all lung cancers and is often rapidly resistant to chemotherapy resulting in poor clinical outcomes. Treatment has changed little for decades, but a study at The University of Texas MD Anderson Cancer Center offers a potential explanation for why the disease becomes chemoresistant, and a possible avenue to explore new […]

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Massive single-cell survey of kidney cell types reveals new paths to disease

The kidney is a highly complex organ – far beyond a simple filter. Its function requires intricate interactions between many highly specialized cell types to extract waste, balances body fluids, form urine, regulate blood pressure, and secrete hormones. New research from a team in the Perelman School of Medicine at the University of Pennsylvania shines a light on specific cell […]

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