Protective effects of ADM-RAMP2 system make it a new therapeutic target for retinal vein occlusion

A clot in the retinal vein can lead to severe and irreversible loss of vision. In a report in the American Journal of Pathology investigators utilize a newly developed model of central retinal vein occlusion (CRVO) in mice that mimics many of the clinical features of CRVO in humans to study the pathologic effects of retinal occlusion and demonstrate the […]

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Why screen time can disrupt sleep—scientists uncover how certain retinal cells respond to artificial illumination

For most, the time spent staring at screens—on computers, phones, iPads—constitutes many hours and can often disrupt sleep. Now, Salk Institute researchers have pinpointed how certain cells in the eye process ambient light and reset our internal clocks, the daily cycles of physiological processes known as the circadian rhythm. When these cells are exposed to artificial light late into the […]

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Microglia protect sensory cells needed for vision after retinal detachment

A research team at Massachusetts Eye and Ear has shown that microglia, the primary immune cells of the brain and retina, play a protective role in response to retinal detachment. Retinal detachment and subsequent degeneration of the retina can lead to progressive visual decline due to photoreceptor cell death, the major light-sensing cell in the eye. In a report published […]

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Researchers test stem cell-based retinal implant for common cause of vision loss

Physicians and researchers at the USC Roski Eye Institute have collaborated with other California institutions to show that a first-in-kind stem cell-based retinal implant is feasible for use in people with advanced dry age-related macular degeneration. The results of their phase I/IIa study, which was funded in part by the California Institute for Regenerative Medicine, were published today in Science […]

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