Probing the role of an inflammation resolution sensor in obesity and heart failure

After heart attack injury, several fatty-acid-derived bioactive molecules—including one called resolvin D1—play an essential signaling role to safely clear inflammation and help repair heart muscle. The mechanism of how this resolution occurs is not well-understood. There is a receptor on the surface of many immune cells called ALX/FRP2, and in models of atherosclerosis, ALX/FPR2 is known to act as a […]

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MRI resolution enhanced at cellular level

Neuroscience researchers have long used Magnetic Resonance Imaging to study the basic structure of the brain in health and disease, but MRI scanners can’t typically provide insights at the cellular level. In an MRI image, each voxel—the 3-D equivalent of a pixel—represents tens of thousands of brain cells. A breakthrough study led by the Mark and Mary Stevens Neuroimaging and […]

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