Research team documents potential new treatment path for breast cancer

Immunotherapies that take off the “brakes” on the adaptive anti-tumor response have worked well in melanoma and lung cancer but less so in breast cancers. That could change. A Vanderbilt team led by John Wilson, assistant professor of chemical and biomolecular engineering, and Rebecca Cook, associate professor of cell and developmental biology, activated innate immunity in breast cancer cells and […]

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Research suggests path to vaccine or drug for late-onset Alzheimer’s

UT Southwestern researchers have succeeded in neutralizing what they believe is a primary factor in late-onset Alzheimer’s disease, opening the door to development of a drug that could be administered before age 40, and taken for life, to potentially prevent the disease in 50 to 80 percent of at-risk adults. Apolipoprotein E (ApoE) is a protein that carries fatty substances […]

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Research shows how service dogs can help veterans with PTSD

For veterans struggling with post-traumatic stress disorder, service dogs might be able to offer both behavioral and physiological benefits to help counter some of those symptoms, according to research that is being led by the Purdue College of Veterinary Medicine. Maggie O’Haire, assistant professor of human-animal interaction in the College of Veterinary Medicine, is at the forefront of the research […]

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Research shows signalling mechanism in the brain shapes social aggression

Duke-NUS researchers have discovered that a growth factor protein, called brain-derived neurotrophic factor (BDNF), and its receptor, tropomyosin receptor kinase B (TrkB) affects social dominance in mice. The research has implications for understanding the neurobiology of aggression and bullying. “Humans and rodents are social animals. Our every interaction follows rules according to a social hierarchy. Failure to navigate this hierarchy […]

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Research digs up the fat-fighting power of clays

Investigating how clay materials can improve drug delivery, UniSA researcher and Ph.D. candidate, Tahnee Dening serendipitously discovered that the clay materials she was using had a unique ability to “soak up” fat droplets in the gut. Dening says this accidental discovery could potentially be a cure for obesity. “It’s quite amazing really,” Dening says. “I was investigating the capacity of […]

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Research discovers new channel-gating mechanism

Computational biophysicists are not used to making discoveries, says Jianhan Chen at the University of Massachusetts Amherst, so when he and colleagues cracked the secret of how cells regulate Big Potassium (BK) channels, they thought it must be a computational artifact. But after many simulations and tests, they convinced themselves that they have identified the BK gating mechanism that had […]

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Research shows it’s possible to reverse damage caused by aging cells

What’s the secret to aging well? University of Minnesota Medical School researchers have answered it- on a cellular level. Aging starts in our cells, and those aging cells can hasten cellular senescence, leading to tissue dysfunction and related health impacts. New research involving University of Minnesota Medical School faculty Paul D. Robbins and Laura J. Niedernhofer, recently published in Nature […]

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