Cross-species prion adaptation depends on prion replication environment

A hamster prion that replicated under conditions of low RNA levels in mouse brain material resulted in altered disease features when readapted and transmitted back to hamsters, according to new research presented in PLOS Pathogens by Elizaveta Katorcha of the University of Maryland School of Medicine, Baltimore, and colleagues. Prions are abnormal proteins that can induce normal versions of the […]

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