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Research led by the Centre for Addiction and Mental Health (CAMH) published in the Journal of Clinical Investigation points to a groundbreaking discovery about a new potential treatment and prevention for post-traumatic stress disorder (PTSD). The research team, led by Dr. Fang Liu, Senior Scientist and Head of Molecular Neuroscience in CAMH’s Campbell Family Mental Health Research Institute, and Professor […]
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QIMR Berghofer researchers have discovered a potential new cancer immunotherapy target that involves switching off a regulatory cell to stop tumors growing and spreading. The study findings have been published today in Cancer Discovery, a journal of the American Association for Cancer Research. Senior researcher and head of QIMR Berghofer’s Cancer Immunoregulation and Immunotherapy Laboratory, Associate Professor Michele Teng, said […]
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A research team led by scientists from the Consortium for Fibrosis Research & Translation (CFReT) at the University of Colorado School of Medicine has identified a potential target for treating heart failure related to fibrosis. Fibrosis is a wound-healing response after tissue injury or stress. Cardiac fibrosis can cause abnormal stiffening of the heart, contributing to the pathogenesis of heart […]
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Immediately following severe burns, bacteria reach the wound from different sources, including the patient’s skin, gastrointestinal tract, respiratory tracts and health care-related human contact. Within the wound, bacteria multiply, establish an infection and move from the infected burn wound into the bloodstream, causing serious complications like sepsis, multiple-organ failure and death. In modern burn units, more than 50% of deaths […]
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Researchers are hopeful that new strategies could emerge for slowing the growth and recurrence of the most common primary brain cancer in adults, glioblastoma, based on the results of a study published today in Cancer Research. Research led by Toronto’s St. Michael’s Hospital and The Hospital for Sick Children (SickKids) suggests the protein ID1 is critical to tumour initiation and […]
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Since its discovery in 1999, Nipah virus has been reported almost yearly in Southeast Asia, with Bangladesh and India being the hardest hit. In a new study, published today in PLoS Neglected Tropical Diseases, scientists used machine learning to identify bat species with the potential to host Nipah virus, with a focus on India—the site of a 2018 outbreak. Four […]
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Researchers from Duke-NUS Medical School, Singapore General Hospital (SGH) and Lion TCR have demonstrated that they were able to engineer HBV-specific T cells, a type of immune cells found in the body, to treat Hepatocellular carcinoma (HCC), a commonly occurring liver cancer. The treatment was also individualised, as T cells that were engineered were specific to the patients. The approach […]
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Researchers may have found a way to improve a common treatment for post-traumatic stress disorder (PTSD) by changing how the brain learns to respond less severely to fearful conditions, according to research published in Journal of Neuroscience. The study by researchers at The University of Texas at Austin Dell Medical School suggests a potential improvement to exposure therapy—the current gold […]
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The MYCN oncogene has long been known to be a key cause of a number of deadly solid tumour cancers, including neuroblastoma, which claims more lives of children under the age of 5 than any other cancer. Neuroblastoma is the most common solid tumour found in young children. In up to 25% of cases, the tumours contain an increased number […]
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Immunotherapies that take off the “brakes” on the adaptive anti-tumor response have worked well in melanoma and lung cancer but less so in breast cancers. That could change. A Vanderbilt team led by John Wilson, assistant professor of chemical and biomolecular engineering, and Rebecca Cook, associate professor of cell and developmental biology, activated innate immunity in breast cancer cells and […]
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