Bioelectronic implant could prevent opioid deaths

Researchers are developing a novel, implantable device that can sense the effects of a potentially fatal level of ingested opioids and then automatically and immediately deliver a life-saving dose of naloxone. The interdisciplinary research team, led by Northwestern University and Washington University at St. Louis, recently received a grant from the National Institutes of Health’s Helping to End Addiction Long-term […]

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What we don’t know about prenatal opioid exposure

Pregnancy can be a time of anxious uncertainty, particularly if there are any risks of complications. The question always arises, from parents, grandparents, friends and others: “Will the baby be OK?” In cases where the baby has been exposed to opioids in the womb, the answer is unclear. As part of a National Institutes of Health initiative to study the […]

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New opioid speeds up recovery without increasing pain sensitivity or risk of chronic pain

Morphine and other opioid-based painkillers are very effective at treating pain initially, but studies have shown that the drugs can make patients more pain-sensitive, prolonging their discomfort and increasing their risks of developing chronic pain. A new type of opioid developed by researchers at Tulane University and the Southeast Louisiana Veterans Health Care System doesn’t have this side effect and […]

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Nonmedical Rx opioid use in teens linked to parental use

(HealthDay)—Nonmedical prescription opioid (NMPO) use in adolescents is associated with parental NMPO use and with smoking and parent-adolescent conflict, according to a study published online Feb. 25 in Pediatrics. Pamela C. Griesler, Ph.D., from Columbia University in New York City, and colleagues examined the correlation between self-reported parental and adolescent lifetime NMPO use using data for 35,000 parent-child dyads with […]

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Opioid gene variant in adolescents reduces reward, may increase later substance abuse risk

Adolescents with a particular variant of an opioid receptor gene have less response in a part of prefrontal cortex that evaluates rewards, compared to those with the other version of the gene, say researchers at Georgetown University Medical Center (GUMC). For the study, presented Monday at Neuroscience 2018, the annual meeting of the Society for Neuroscience (abstract #7517), the investigators […]

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Conflicting guidance on opioid prescribing can jeopardize pain management for patients with cancer

Persistent pain and recurrent episodes of pain are common for those who are living with cancer, or for those undergoing cancer treatment. When used properly, prescription opioids have long been known to help combat pain experienced by people with cancer. In the face of the worsening opioid epidemic, clinical guidelines have been published by multiple agencies to improve the way […]

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