How to enable light to switch on and off therapeutic antibodies

When antigens such as a virus or bacteria invade our body, the immune system springs into action: it creates antibodies that stick to the antigens so that they can identify and destroy the intruders. Did you know that these Y-shaped proteins, AKA antibodies, have been revolutionizing the treatment of cancer, inflammatory disease and autoimmune disease, and many others? Therapeutic antibodies […]

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Should scores on mild cognitive impairment tests be adjusted for sex?

Using sex-specific scores on memory tests may change who gets diagnosed with mild cognitive impairment (MCI) by 20 percent, with possibly more women and fewer men being diagnosed, according to a study published in the October 9, 2019, online issue of Neurology, the medical journal of the American Academy of Neurology. Mild cognitive impairment, a precursor to dementia, is when […]

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New research sheds light on how happy couples argue

In marriage, conflict is inevitable. Even the happiest couples argue. And research shows they tend to argue about the same topics as unhappy couples: children, money, in-laws, intimacy. So, what distinguishes happy couples? According to “What are the Marital Problems of Happy Couples? A Multimethod, Two-Sample Investigation,” a study published this August in Family Process, it is the way happy […]

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Algorithm based on response, biology guides neuroblastoma therapy

(HealthDay)—Use of a response- and biology-based treatment algorithm for intermediate-risk neuroblastoma is associated with excellent survival and reduces treatment for some patients, according to a study published online Aug. 6 in the Journal of Clinical Oncology. Clare J. Twist, M.D., from the Roswell Park Cancer Institute in Buffalo, New York, and colleagues enrolled 404 evaluable patients between 2007 and 2011 […]

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New method classifies brain cells based on electrical signals

For decades, neuroscientists have relied on a technique for reading out electrical “spikes” of brain activity in live, behaving subjects that tells them very little about the types of cells they are monitoring. In a new study, researchers at the University of Tuebingen and MIT’s Picower Institute for Learning and Memory demonstrate a way to increase their insight by distinguishing […]

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