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(HealthDay)—Older age is associated with poorer course of major depressive disorder (MDD), according to a study published online June 7 in The Lancet Psychiatry. Roxanne Schaakxs, Ph.D., from VU University Medical Center in Amsterdam, and colleagues obtained data for 1,042 participants with MDD at baseline, who had data available at baseline and two-year follow-up. The primary outcome was the two-year […]
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Flu killed more U.S. children in the past year than during any other regular flu season in recent history. Health officials on Friday said they’ve received reports of 172 pediatric flu deaths since October. An average season sees about 110. There were more deaths in 2009-2010, when a rare flu pandemic occurred involving a new strain. More than 300 children […]
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Dementia in any form is a heartbreaking disease that can take away the capacity for thinking and making judgements. To save face, people with dementia often pretend to know answers to questions, even when they really don’t. This often hides the severity of the disease and exacerbates the fears and frustrations of the people who care for them. The act […]
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Zika virus is an arbovirus transmitted by the Aedes aegypti mosquito, but it can also be transmitted by sexual contact and blood transfusion. Adult patients infected by Zika usually present only mild symptoms over a few days, such as rashes, conjunctivitis, arthralgia and mild fever. However, the outbreak of Zika virus in Brazil in 2015 first showed the world that […]
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Having a demanding job and little control over it is associated with an increased risk of premature death in men with coronary heart disease, stroke, or diabetes, according to an observational study tracking more than 100000 men and women with and without cardiometabolic disease from Finland, France, Sweden, and the UK for almost 14 years, published in The Lancet Diabetes […]
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Pancreatic cancer patients treated with chemotherapy and radiotherapy before surgery may live longer than those who have immediate surgery, according to unpublished clinical trial results. The research, funded by the Dutch Cancer Society, looked at patients who had pancreatic cancer that could be removed by surgery because their cancer had not spread from the pancreas. Patients who had chemoradiotherapy before […]
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People who live with type 1 diabetes for very long duration show signs of mild decreases in cognitive abilities, primarily in memory, compared to those who don’t have the disease, Joslin Diabetes Center researchers have shown. The study compared Joslin 50-year Medalists, who have lived successfully with type 1 diabetes for at least that long, with other people of similar […]
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Early phase clinical trial results presented today at the American Society of Clinical Oncology (ASCO) Annual Meeting 2018 of 258 patients with IDH1+ acute myeloid leukemia (AML) treated with the IDH1 inhibitor ivosidenib show an overall response rate of 41.9 percent, with median progression free survival of 8.2 months. Twenty-four percent of patients achieved a complete response. The gene IDH1 […]
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Ivosidenib, an experimental drug that inhibits a protein often mutated in several cancers has been shown to be safe, resulting in durable remissions, in a study of acute myeloid leukemia (AML) with relapsed or refractory disease. The multi-center Phase I trial, led by researchers at The University of Texas MD Anderson Cancer Center, was designed to determine ivosidenib’s safety and […]
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People with a gene variant called APOE4 have a higher risk of developing late-onset Alzheimer’s disease: APOE4 is three times more common among Alzheimer’s patients than it is among the general population. However, little is known about why this version of the APOE gene, which is normally involved in metabolism and transport of fatty molecules such as cholesterol, confers higher […]
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