Rewriting our understanding of gastric tumors

The immune system can be an important ally in the fight against cancer. A study from McGill scientists published today in Science suggests that the reverse may also be true—that abnormal inflammation triggered by the immune system may underlie the development of stomach tumours in patients with a hereditary cancer syndrome known as Peutz-Jeghers Syndrome (PJS). The findings are likely […]

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Traumatic brain injury: Discovery of two molecules could lead to new drug treatments

After 10 years of research, a Rutgers-led team of scientists has identified two molecules that protect nerve cells after a traumatic brain injury and could lead to new drug treatments. The molecules promote full recovery after traumatic brain injury (TBI) in mice, according to the study published online in Neurobiology of Disease. Traumatic brain injury is the leading cause of […]

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Next-generation ALS drug silences inherited form of the disease in animal models

NIH-funded researchers delayed signs of amyotrophic lateral sclerosis (ALS) in rodents by injecting them with a second-generation drug designed to silence the gene, superoxide dismutase 1 (SOD1). The results, published in the Journal of Clinical Investigation, suggest the newer version of the drug may be effective at treating an inherited form of the disease caused by mutations in SOD1. Currently, […]

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Half of female students experience psychological distress, study shows

For the first time, just over 50 per cent of female students in Ontario show signs of moderate to serious psychological distress, according to the latest Ontario Student Drug Use and Health Survey (OSDUHS), released by Toronto’s Centre for Addiction and Mental Health (CAMH). Psychological distress—which refers to symptoms of anxiety or depression—has been rising steadily among all Ontario students […]

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Are neurological disorders the result of brain evolution mistakes?

A team of researchers affiliated with several institutions in Australia has proposed that some neurological disorders might have their roots in evolutionary mistakes. In their paper published in the journal Nature Neuroscience, the group describes their ideas and possible paths of research moving forward. As scientists delve ever deeper into our brains as part of an effort to understand how […]

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A new model to estimate lifetime risk of atherosclerotic cardiovascular disease

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality and also contributes to huge health care expenditures in China. Therefore, accurate and early identification of high-risk individuals is important for CVD prevention. The China-PAR (Prediction for atherosclerotic CVD (ASCVD) Risk in China) project generated equations with excellent capacity to predict lifetime risk for ASCVD by incorporating four large […]

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Study provides insight into how dying neurons control eating behaviors of the brain microglia

A new Mount Sinai study, published July 23 in the journal Nature Neuroscience, provides important insight into how microglia, cells that form a branch of the immune system inside the brain, go about their job of clearing out dying and non-functional neurons—and how they sometimes mistakenly attack healthy neurons, an event that can play a role in neurodegenerative diseases like […]

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