Circadian clock and fat metabolism linked through newly discovered mechanism

The enzyme Nocturnin, which governs daily tasks such as fat metabolism and energy usage, works in an entirely different way than previously thought, reported a team of researchers at Princeton University. The newly discovered mechanism reveals the molecular link between the enzyme’s daily fluctuations and its energy-regulating role in the body, according to a study published this week in Nature […]

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Newly single? How to beat the breakup blues

Whether you dated for weeks, months or years—when it ends, you can experience a range of emotions and feel a little uncertain about what’s next. Research even shows the pain from a breakup can activate pain receptors in our brain the same way that physical injuries do. When you’re feeling down and out, how do you beat the breakup blues? […]

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Newly identified drug target in rheumatoid arthritis paves way for development of new therapies

University of Melbourne researchers have identified a protein involved in rheumatoid arthritis-induced inflammation that could lead to new drug treatments for people who do not respond to current therapies. Arthritis is Australia’s most common chronic disease and affects more than 3.5 million people. Rheumatoid arthritis (RA) affects about one per cent of the population and is one of the most […]

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Newly characterized molecule offers possibilities for novel Alzheimer’s treatments

Alzheimer’s disease is an increasingly prevalent, neurodegenerative condition that erodes memory and other cognitive functions. Treatments for this complex disease have been elusive, although researchers have previously uncovered its main biological features: amyloid-beta plaques and tau tangles. A study by researchers from Brigham and Women’s Hospital (BWH), recently published in Acta Neuropathologica, investigated lesser-known molecules involved in tauopathies like Alzheimer’s. […]

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Newly identified genetic markers classify previously undetermined glioblastoma tumors

Most glioblastoma tumors are marked by one or two broad mutation patterns, but about 20 percent of the lethal brain tumors have biomarkers that cannot be identified.  Now scientists at Duke Cancer Institute have identified mutations for the vast majority of the remaining 20 percent of uncharacterized tumors, which tend to be especially lethal. The findings indicate that these mutations […]

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