Study links BAP1 protein to tumor suppression in kidney, eye, bile duct and mesothelioma cancers

Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a form of cell death called ferroptosis, opening up a potential new area of therapy research. Findings from the study, led by Boyi Gan, Ph.D., associate […]

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New study provides rationale for use of a multi-target anticancer drug in patients with malignant pleural mesothelioma

The multi-target small molecule anticancer drug nintedanib shows promising effectiveness in stopping the growth of human malignant pleural mesothelioma, a fatal thoracic tumor, in preclinical models, according to a new study published jointly by researchers in Austria, Germany and Hungary. Malignant pleural mesothelioma is a particularly aggressive tumor that occurs in the lining that covers the lungs. It typically results […]

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