Elucidation of functional mechanism of ‘love hormone,’ oxytocin, at molecular level

Oxytocin is essential in activities of the social brain such as trust and love and in maternal bonding behaviors. It is produced in the brain and secreted into the circulation. Here, by analyzing maternal behaviors of RAGE gene-manipulated mice, oxytocin was found to be transported back to the brain, crossing the blood-brain barrier (BBB), an extremely effective barrier, by binding […]

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A new machine learning model can classify lung cancer slides at the pathologist level

Machine learning has improved dramatically in recent years and shown great promise in the field of medical image analysis. A team of research specialists at Dartmouth’s Norris Cotton Cancer Center have utilized machine learning capabilities to assist with the challenging task of grading tumor patterns and subtypes of lung adenocarcinoma, the most common form of the leading cause of cancer-related […]

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Encouraging more health workers to have flu jab needs new approach that connects on an emotional level

Persuading more health workers to have the flu jab to protect themselves and their patients cannot be done through facts and statistics alone, new research by a leading behavioural scientist from Kingston University has revealed. Instead it demands a new approach that connects with people emotionally to sustain immunisation rates at effective levels. Nearly one third of nurses, GPs and […]

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MRI resolution enhanced at cellular level

Neuroscience researchers have long used Magnetic Resonance Imaging to study the basic structure of the brain in health and disease, but MRI scanners can’t typically provide insights at the cellular level. In an MRI image, each voxel—the 3-D equivalent of a pixel—represents tens of thousands of brain cells. A breakthrough study led by the Mark and Mary Stevens Neuroimaging and […]

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PSA level three months after radiation tx may predict outcome

(HealthDay)—Prostate-specific antigen (PSA) levels three months after radiotherapy (RT) are strong markers of prostate cancer outcomes for patients with intermediate- and high-risk disease, according to a study published online May 4 in Cancer. Alex K. Bryant, from University of California at San Diego, and colleagues used Veterans Affairs data to identify 5,783 patients with intermediate-risk or high-risk localized prostate cancer […]

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Characterizing ‘keyhole’ is first step to fighting obesity at cellular level

An international team has uncovered the potential to beat obesity at the cellular level, characterizing for the first time a complex, little-understood receptor type that, when activated, shuts off hunger. Jens Meiler, professor of chemistry and pharmacology at Vanderbilt University, said pharmaceutical companies long have attempted to develop a small-molecule drug that could do just that. But until now, nobody […]

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