CPR is key to survival of sudden cardiac arrest

Cardiopulmonary resuscitation increases the possibility of surviving sudden cardiac arrest. But it’s not just trained professionals who can jump in to perform CPR. There are simple, life-saving steps any bystander can take. “We think it should be a basic life skill,” such as knowing to call 911 when there’s a fire, said Dr. Clifton Callaway, a professor and executive vice […]

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A key switch in biological clocks

Just as we abide by an external time schedule to eat, sleep, and go to work, our body is similarly dictated by internal clocks. Known as circadian rhythms, these daily cycles keep us on a regular 24-hour day and are involved in numerous aspects of our well-being. When these biological clocks fail to work as they should, our bodies are […]

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Rare plant compounds could hold key to treating resistant hypertension

Researchers have discovered new natural compounds in a fig plant species native to Malaysia that could lead to improved treatment for resistant hypertension. Dr. Kuan Hon Lim and his team from the University of Nottingham Malaysia have isolated a new class of natural compounds from a local fig plant species that induce vasodilation in aorta tissue, meaning the compounds have […]

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PARP-1 may be key to effectiveness of PARP inhibitors, and now researchers can image it

Penn Medicine researchers have used CRISPR/Cas9 gene editing technology to isolate a key genetic feature that could cause resistance to PARP inhibitors in patients with ovarian cancer—and they’ve also proven they have a way to see that feature using PET imaging. The team found PARP inhibitors—a type of targeted therapy that kills cancer cells with mutations in their DNA repair […]

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Scientists discover sweet spot of activity in immune system key to fighting cancer

Scientists at the University of Southampton have shown how stimulating a specific location on the surface of immune cells can be targeted with antibodies to help in their fight against cancer. The new work concerns a receptor called CD40 found of the surface of certain immune cells which regulates their activity. The CD40 receptors are normally dispersed over the surface […]

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