Recorded penicillin allergy linked to increased risk of ‘superbug’ infections

Patients who have a penicillin allergy recorded in their medical records are at an increased risk of developing the drug resistant ‘superbug’ infection MRSA and healthcare-associated infection C difficile, finds a study published by The BMJ today. The risk is largely due to the use of more ‘broad spectrum’ antibiotics as alternatives to penicillin, which may be fuelling the development […]

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Clostridium difficile infections have decreased 36 percent in Canadian hospitals

Rates of C. difficile infections have decreased 36% in hospitals across Canada, although the virulent NAP1 strain associated with severe illness and deaths is the most common strain, according to research published in CMAJ (Canadian Medical Association Journal) Clostridium difficile is the most common infectious cause of diarrhea in hospitalized patients in developed countries, causing severe illness and occasionally death. […]

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Cell-free DNA profiling informative way to monitor urinary tract infections

Using shotgun DNA sequencing, Cornell University researchers have demonstrated a new method for monitoring urinary tract infections (UTIs) that surpasses traditional methods in providing valuable information about the dynamics of the infection as well as the patient’s biological response. The technique is detailed in the paper “Urinary cell-free DNA is a versatile analyte for monitoring infections of the urinary tract,” […]

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Mixed progress on drug resistance in A. baumannii infections in children

In the first national study of the prevalence of antibiotic-resistant Acinetobacter baumannii infections in children across the US, researchers from Center for Disease Dynamics, Economics, & Policy (CDDEP) in Washington, DC and Rush University in Chicago, IL examined national and regional trends of antibiotic resistance in clinical specimens over a 13-year period. While there was an overall increase between 1999 […]

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Infections could trigger stroke in pregnant women during hospital delivery

Pregnant women who have an infection when they enter the hospital for delivery might be at higher risk of having a stroke during their stay, according to new research. The study, published Friday in the journal Stroke, tried to determine if infections contribute to stroke risk during peripartum, a term meaning shortly before or after childbirth. While maternal strokes are […]

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A third of bacterial infections in patients with cirrhosis across the world are multi-drug resistant

A worldwide study initiated to investigate the epidemiology and outcomes of bacterial infections in hospitalized patients with liver cirrhosis has reported a prevalence of multi-drug-resistant (MDR) bacteria of 34% and significant regional differences in the risk of developing a multi-drug-resistant infection. Research teams from 46 centres across the world collaborated in this international study, which was promoted by the International […]

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