Developmental disabilities reported in HIV-positive children in South Africa

HIV-positive children in South Africa are more likely to have developmental disabilities compared to children who are HIV negative, according to researchers at Columbia University’s Mailman School of Public Health. HIV-positive children ages 4 to 6 had nearly four times the odds of delays in sitting, standing, walking, and speaking, and more than twice the odds of a hearing disability […]

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Living in areas with less sun may increase your risk of OCD

Living at higher latitudes, where there is also less sunlight, could result in a higher prevalence rate of obsessive compulsive disorder (OCD), according to new research from Binghamton University, State University of New York. “The results of this project are exciting because they provide additional evidence for a new way of thinking about OCD,” said Meredith Coles, professor of psychology […]

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Higher doses of rifampin appear more effective in fighting tuberculosis without increasing risk of adverse events

Higher daily doses of rifampin, a cornerstone of tuberculosis treatment, killed more TB bacteria in sputum cultures, and the higher doses did so without increasing the adverse effects of treatment, according to a randomized controlled trial published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine. In “Efficacy and Safety of High-Dose Rifampin in Pulmonary […]

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New treatment to reverse drug resistance in some cancers

University of Queensland researchers have discovered how to reverse drug resistance in skin and mouth squamous cell carcinomas. UQ Diamantina Institute Associate Professor Nicholas Saunders said squamous cell carcinomas was curable when diagnosed early but difficult to eradicate once the cancer spread. “This cancer of the skin and mouth kills approximately 1,400 Australians each year,” Dr. Saunders said. “The drugs […]

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Drug treatment has profound effect on cerebral malaria in mice

A potentially new way of treating cerebral malaria has been discovered by scientists at the Universities of Manchester and Glasgow, in a study using mice. The authors found that inhibiting a complex called the inflammasome, at the same time as delivering anti-malarial drugs, reduced mortality from experimental cerebral malaria in mice. The research, published in PNAS and funded by the […]

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Usutu, an African virus under surveillance in Europe

“This is a virus transmitted by mosquitoes that circulates between birds. It can attack the nervous system of certain birds, such as blackbirds, and cause significant mortality. It was first observed in southern Africa, in Swaziland, in 1959,” says Serafin Gutierrez, a virology researcher with CIRAD”S ASTRE research unit. The virus, called Usutu, belongs to the genus Flavivirus, which includes […]

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Proteins found in semen increase the spread of Ebola virus infection

Protein fragments, called amyloid fibrils, in human semen significantly increase Ebola virus infection and protect the virus against harsh environmental conditions such as heat and dehydration. Researchers from the Perelman School of Medicine at the University of Pennsylvania report these findings in a study published this week in the Proceedings of the National Academy of Sciences (PNAS). Although Ebola is […]

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Clostridium difficile infections have decreased 36 percent in Canadian hospitals

Rates of C. difficile infections have decreased 36% in hospitals across Canada, although the virulent NAP1 strain associated with severe illness and deaths is the most common strain, according to research published in CMAJ (Canadian Medical Association Journal) Clostridium difficile is the most common infectious cause of diarrhea in hospitalized patients in developed countries, causing severe illness and occasionally death. […]

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Watching stem cells repair spinal cord in real time

Monash University researchers have restored movement and regenerated nerves using stem cells in zebra fish where the spinal cord is severely damaged. The research, presented at the International Society for Stem Cell Research conference in Melbourne this week, raises the possibility that these same stem cells could be triggered in human patients who have suffered paralysing damage to their nervous […]

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