in Archives - Page 27 of 51 - Family Medicine News

Duvelisib has marked response, survival benefit in difficult-to-treat leukemia and lymphoma

05.10.2018 Health Problems

For some patients with difficult-to-treat leukemia and lymphoma, the investigational oral medicine duvelisib may significantly improve disease outcomes, according to phase III trial data published today in the journal Blood. The DUO trial studied the head-to-head comparison of duvelisib versus ofatumumab, an approved standard-of-care chemotherapy for relapsed or treatment-resistant chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). According to […]

Family history linked to early-onset A-fib in minorities

04.10.2018 Health Problems

(HealthDay)—Probands of African or Hispanic/Latino descent with early-onset atrial fibrillation (EOAF) are more likely than European Americans to have a first-degree relative with AF, according to a study published online Sept. 21 in JAMA Network Open. Zain Alzahrani, M.D., from the University of Illinois at Chicago, and colleagues conducted a cohort study to examine the role of family history in […]

Study: Improvement in glycemic parameters by adding dapagliflozin to metformin in T2D

04.10.2018 Health Problems

Researchers used continuous glucose monitoring (CGM) to assess the effects of adding dapagliflozin to a regimen of either metformin or insulin in patients with type 2 diabetes (T2D) and found significant reductions in mean glucose and other glycemic factors, with greater improvements seen in patients taking metformin compared to insulin. The design and results of this trial are published in […]

Media violence, impulsivity and family conflict tied to aggressive behaviors in teenagers

27.09.2018 Health Problems

Teenagers exposed to TV and film violence and high levels of household conflict are at risk of engaging in aggressive behaviors, according to a new study by researchers at three U.S. universities. Especially prone to aggressive tendencies are those who also have high levels of impulsivity, the six-member research team reported in a study published online ahead of print in […]

Clinical trial investigators violate EU regulations—entries in EU Register are incomplete

25.09.2018 Health Problems

According to EU legislation, clinical trials must be prospectively registered in the European Union Clinical Trials Register (EUCTR) and the main results must be reported there one year after completion of the trial. The information is thus publicly available. But in fact, results are only reported for half of drug trials (49.5 percent). According to an analysis recently published in […]

Prosthetic valve mismatches common in transcatheter valve replacement, ups risk of death

24.09.2018 Health Problems

In the largest multi-institutional study to date, led by researchers from Penn Medicine, the team found that among patients who underwent a transcatheter aortic valve replacement (TAVR), a high number experienced severe and moderate cases of prosthesis-patient mismatch (PPM)—meaning the implanted heart valve is too small for the patient which can lead to inadequate blood flow. The team also found […]

Repeat CT common in peds traumatic epidural hematoma

22.09.2018 Health Problems

(HealthDay)—For children with traumatic epidural hematomas (EDHs), repeated computed tomography (CT) imaging is common, but rarely impacts management, according to a study published in the September issue of Pediatrics. Brian F. Flaherty, M.D., from the University of Utah in Salt Lake City, and colleagues conducted a retrospective cohort study involving 184 subjects aged 0 to 18 years who had a […]

Nerve cells in the human brain can ‘count’

21.09.2018 Health Problems

How do we know if we’re looking at three apples or four? Researchers at the Universities of Bonn and Tübingen are now one step closer to answering this question. They were able to demonstrate that some brain cells fire mainly for quantities of three, others for quantities of four and others for other quantities. A similar effect can be observed […]

A new app enables a smartphone to ID bacteria in just one hour

20.09.2018 Health Problems

In a potential game changer for the health care industry, a new cell phone app and lab kit now allow a smartphone to identify bacteria from patients anywhere in the world. With the new app, doctors will be able to diagnose diseases and prescribe the appropriate antibiotic within a one-hour office visit, meaning faster recovery—and lower treatment costs—for patients. Developed […]

Zombie cells found in brains of mice prior to cognitive loss

19.09.2018 Health Problems

Zombie cells are the ones that can’t die but are equally unable to perform the functions of a normal cell. These zombie, or senescent, cells are implicated in a number of age-related diseases. And with a new letter in Nature, Mayo Clinic researchers have expanded that list. In a mouse model of brain disease, scientists report that senescent cells accumulate […]

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