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Researchers from NC State and the University of São Paulo want to reduce Leptospirosis in Brazil, where the disease is a major public health concern. So they’ve developed a risk-based priority index for all 26 Brazilian states, to help public health officials target areas most likely to be affected. The priority index ranks the states according to which ones would […]
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Results from a phase 2 randomised trial suggest that a new investigational antibiotic is as effective as the current standard-of-care antibiotic for the treatment of complicated urinary tract infections (UTIs) caused by several multidrug resistant Gram-negative bacteria. The findings, published in The Lancet Infectious Diseases, indicated that patients treated with the siderophore-based drug, cefiderocol, had a higher and more sustained […]
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What causes some adolescents to thrive while other teenagers struggle with substance abuse and mental health? Through years of research, the scientists who study development and the clinicians who treat troubled teenagers have developed a list of risk factors that predict the problems faced by adolescents. The Robert Wood Johnson Foundation, an influential philanthropic organization that focuses on health, recently […]
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A new study by the University of the West of England (UWE Bristol) into work going on in Gloucestershire schools shows that young people are becoming more responsible for looking after their own health. Facts4Life is one of a suite of health and wellbeing programmes and interventions being delivered in Gloucestershire schools. The programme, run by a GP and a […]
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(HealthDay)—New Jersey health officials on Wednesday confirmed the deaths of seven children following infection with an adenovirus—a member of the same viral family that causes the common cold. Eleven other children are infected, and all cases occurred at the same health care facility, the Wanaque Center for Nursing and Rehabilitation in Haskell, according to N.J. Commissioner of Health Dr. Shereef […]
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The most effective way to prevent life-threatening complications of extreme hypertension in African-Americans with diabetes is to better control their blood pressure, according to a Rutgers study, the largest of its kind. The study, which appears in Clinical and Experimental Hypertension, included 783 diabetic and 1,001 non-diabetic patients from a New Jersey hospital emergency department that serves predominantly African-American communities. […]
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A child’s blood pressure could indicate cognition problems into adulthood, according to a new study suggesting the cardiovascular connection to cognitive decline could begin much earlier in life than previously believed. The findings may provide a window into the roots of dementia, for which high blood pressure is considered a risk factor. “We wondered is there perhaps some signal early […]
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We make judgements quite rationally or “by the gut.” Not only experience and relevant information play an important role, but also our preferences. A study by the Max Planck Institute for Metabolism Research in Cologne shows how the reward system in the brain conveys judgements affected by one’s own desires. “In complex, confusing situations, we run the risk of making […]
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Pre-operative treatment with a combination of the immune checkpoint inhibitors nivolumab and ipilimumab achieves major pathological responses in 100 percent of early-stage colon cancers with mismatch repair deficiencies, according to results reported at ESMO 2018 from the first exploratory phase II trial to investigate this approach. Restoring patients’ immune response against cancer cells with checkpoint inhibitors is an established treatment […]
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Duke-NUS researchers have discovered that a growth factor protein, called brain-derived neurotrophic factor (BDNF), and its receptor, tropomyosin receptor kinase B (TrkB) affects social dominance in mice. The research has implications for understanding the neurobiology of aggression and bullying. “Humans and rodents are social animals. Our every interaction follows rules according to a social hierarchy. Failure to navigate this hierarchy […]
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