Cancer risk tools underused in general practice, research shows

Potentially life-saving cancer risk assessment tools are being widely underused by general practices across the UK, according to new research. A team of experts from the University of Exeter’s Medical School has designed a set of risk assessment tools—which can predict the likelihood of undiagnosed cancer based on patients’ symptoms, test results and other clinical information. Now, new NIHR-funded research […]

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AUA: Atenolol linked to drop in low-, intermediate-risk prostate cancer

(HealthDay)—Atenolol is associated with a reduction in incident intermediate- and low-risk prostate cancer (PCa), according to a study presented at the annual meeting of the American Urological Association, held from May 3 to 6 in Chicago. Ali Zahalka, M.D., Ph.D., from the Albert Einstein College of Medicine and Montefiore Medical Center in Bronx, New York, and colleagues conducted a retrospective […]

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Suicide attempts by self-poisoning have more than doubled in teens, young adults

A new study from Nationwide Children’s Hospital and the Central Ohio Poison Center found rates of suicide attempts by self-poisoning among adolescents have more than doubled in the last decade in the U.S., and more than tripled for girls and young women. The study, published online today in the Journal of Pediatrics, evaluated the incidence and outcomes from intentional suspected-suicide […]

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Gender impacts brain activity in alcoholics

Compared to alcoholic women, alcoholic men have more diminished brain activity in areas responsible for emotional processing (limbic regions including the amygdala and hippocampus), as well as memory and social processing (cortical regions including the superior frontal and supramarginal regions) among other functions. In 2015, the National Survey on Drug Use and Health Alcoholism found 15.1 million adults have Alcohol […]

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The glass half-full: How optimism can bias prognosis in serious illness

Most people think of optimism as a good thing—a positive outlook in challenging circumstances. But in reality, it’s a psychological state that can be “contagious” in a bad way. A new study, published in the journal Psycho-Oncology, details how a seriously ill patient’s optimism can impact a clinician’s survival prognosis in palliative care conversations. Senior author Robert Gramling, M.D., D.Sc., […]

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A new clue in the mystery of ALS, frontotemporal dementia

A special focus on rogue proteins may hold future promise in stopping the progression of nerve cell destruction in people who have amyotrophic lateral sclerosis (ALS) or frontotemporal dementia. ALS, a rare but devastating disorder that’s also known as Lou Gehrig’s disease, attacks the body’s nerve cells, resulting in progressive muscle weakness as the neurons degenerate over time. There is […]

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Advance in CAR T-cell therapy eliminates severe side effects

An advance in the breakthrough cancer treatment known as CAR T-cell therapy appears to eliminate its severe side effects, making the treatment safer and potentially available in outpatient settings, a new USC study shows. “This is a major improvement,” said Si-Yi Chen of the USC Norris Comprehensive Cancer Center, professor in the Department of Molecular Microbiology and Immunology at the […]

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Diet high in leucine may fuel breast cancer’s drug resistance

About one in eight women in the United States will develop breast cancer in their lifetime. The vast majority of these cancers rely on the hormone estrogen to grow. Estrogen-receptor positive (ER+) breast cancer tumors are frequently treated with the drug tamoxifen, which blocks the hormone’s effect on the tumor. However, many tumors eventually become resistant to tamoxifen, allowing cancer […]

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