New target for drug intervention in Alzheimer’s disease identified

Scientists at the University of Alabama at Birmingham have identified an enzyme in the brain that may be an intriguing target for interventions against Alzheimer’s disease and other dementias. The researchers suggest that the enzyme, a serine/threonine kinase known as LIMK1, may play an important role in the degradation of dendritic spines, the connections between neurons in the brain. In […]

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More aggressive statin tx needed after heart attack in young patients

(HealthDay)—The majority of young heart attack patients with familial hypercholesterolemia (FH) still have elevated cholesterol levels a year later, according to a study published in the May 21 issue of the Journal of the American College of Cardiology. Avinainder Singh, M.D., from Brigham and Women’s Hospital in Boston, and colleagues used data from the YOUNG-MI registry to assess the prevalence […]

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Deadly tick-borne virus cured with experimental flu drug, in mice

Only a few cases of the newly discovered Bourbon virus have been reported, and two of them ended in death, partly because no specific treatments are available for the tick-borne illness. Now, researchers at Washington University School of Medicine in St. Louis have identified an experimental antiviral drug that cures mice infected with the potentially lethal virus. The drug, favipiravir, […]

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Global burden of mental health in conflict settings

People living in countries that have experienced armed conflict are five times more likely to develop anxiety or depression, a University of Queensland research collaboration has found. UQ School of Public Health researcher Dr. Fiona J Charlson said the study, conducted with the World Health Organisation (WHO) and University of Washington, highlighted the serious effects of war on mental health. […]

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Parents of depressed teens in treatment may also benefit from counseling

Teen depression can affect parents’ marital satisfaction, a new Northwestern Medicine study has found. Parents often seek mental health treatment for a child struggling with depression, but the treatment shouldn’t stop with the depressed teen, suggests the study. The study found that while depressed teens were involved in active treatment, parents’ marriages and parent-child conflict remained stable. Once the teens’ […]

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Team develops test to predict immunotherapy response in kidney cancer

A novel imaging test shows promise for identifying kidney cancer patients most likely to benefit from immunotherapy. In a study published today in the Journal for ImmunoTherapy of Cancer, investigators with the UT Southwestern Medical Center Kidney Cancer Program developed a new test to illuminate kidney cancers that may respond to checkpoint inhibitors. The strategy involved transforming an immunotherapy drug, […]

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