Using light to fight GVHD

Extracorporeal photopheresis (ECP) is used to treat chronic graft-versus-host disease (cGVHD)—a complication of bone marrow or stem cell transplant that occurs when donor cells attack the recipient. How ECP works is unclear, and standardized treatment guidelines have not been established. Vanderbilt medical student Jocelyn Gandelman, Madan Jagasia, MBBS, and colleagues conducted a prospective, multicenter clinical trial of ECP for cGVHD. […]

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