Genetics and Susceptibility to Leprosy

Genetic factors in leprosy involve the human leukocyte antigen (HLA) system as well as non-HLA genes. These genes affect the individual’s susceptibility to the disease, including bacillary transmission and clinical features. The chromosomes involved in these aspects include 6p21, 10p13, 17q22, and 20p13. The markers associated with leprosy are termed MRC1 and are in chromosome 10. This region codes for […]

Continue reading »