Marmosets as the canary in the coal mine for Zika

New research shows small, New World monkeys called marmosets may be an important animal model for emerging viruses with the potential for harmful effects on fetuses. Establishing animal models for emerging diseases, like Zika, is necessary for the development of vaccines, therapies and diagnostics. Results of a study published in the journal Scientific Reports showed pregnant marmosets inoculated with the […]

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New tools could uncover important answers for Alzheimer’s researchers

Alzheimer’s disease currently affects more than 5.5 million Americans and is one of the costliest diseases to treat, according to the Alzheimer’s Association. Characterized by a buildup of plaque in the brain, few animal models exist that researchers could use to study this devastating disorder. Now, a team of researchers from the University of Missouri, publishing in PLOS ONE, developed […]

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3-D printing is transforming care for congenital heart disease

3-D printing is an emerging technology that is impacting the way cardiologists treat patients with congenital heart disease (CHD), according to a review paper published today in JACC: Basic to Translational Science. The prevalence of CHD is approximately nine per 1,000 live births, and overall survival rates have steadily increased for even the most complex diseases; however, these patients face […]

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UNICEF ‘muted’ on tobacco control for children

The tobacco industry manipulated the renowned children’s rights agency UNICEF for more than a dozen years, from 2003 until at least 2016, during which time UNICEF’s focus on children’s rights to a tobacco-free life was reduced, according to previously secret documents uncovered by UC San Francisco. The research appears April 30, 2018, in Pediatrics, the journal of the American Academy […]

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Parents may help prep kids for healthier, less violent relationships

Warm, nurturing parents may pass along strategies for building and maintaining positive relationships to their kids, setting them up for healthier, less-violent romantic relationships as young adults, according to researchers. Researchers found that when adolescents reported a positive family climate and their parents using more effective parenting strategies—like providing reasons for decisions and refraining from harsh punishments—those adolescents tended to […]

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Mouse study identifies new target for human accelerated aging syndrome

Scientists from the University of Cambridge have identified a potential therapeutic target in the devastating genetic disease Hutchinson-Gilford Progeria Syndrome (HGPS), which is characterised by premature ageing. In a paper published today in Nature Communications, scientists provide preclinical data showing that chemical inhibition or genetic deregulation of the enzyme N-acetyltransferase 10 (NAT10) leads to significant health and lifespan gains in […]

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Antibody ‘cocktail’ can prevent Zika infection but is not effective for treatment of fetuses

A “cocktail” of monoclonal antibodies that can prevent Zika virus (ZIKV) infection in primates was not effective for treatment of fetuses, according to a new collaborative study led by a University of Miami Miller School of Medicine research team. “We observed that ZIKV isolated from pregnant women in Rio de Janeiro also causes fetal infection in pregnant macaques. Unfortunately, we […]

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