Study finds rare gain for tough-to-treat pancreatic cancer

Patients with pancreatic cancer that hadn’t spread lived substantially longer on a four-drug combo than on a single standard cancer drug, a rare advance for a tough-to-treat disease, researchers reported Monday. The results indicate the powerful chemotherapy treatment known as folfirinox will likely become standard of care for the minority of patients whose pancreatic cancer is diagnosed early enough to […]

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No new adverse events reported for DTaP vaccination

(HealthDay)—No new or unexpected safety issues have been identified in association with diphtheria-tetanus-acellular pertussis (DTaP) vaccines in the United States, according to a study published online June 4 in Pediatrics. Pedro L. Moro, M.D., M.P.H., from the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues searched the Vaccine Adverse Event Reporting System (VAERS) for U.S. reports of […]

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Positive results for phase 1 trial of ivosidenib against AML

Early phase clinical trial results presented today at the American Society of Clinical Oncology (ASCO) Annual Meeting 2018 of 258 patients with IDH1+ acute myeloid leukemia (AML) treated with the IDH1 inhibitor ivosidenib show an overall response rate of 41.9 percent, with median progression free survival of 8.2 months. Twenty-four percent of patients achieved a complete response. The gene IDH1 […]

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Lipid molecules can be used for cancer growth

When the blood supply is low, cancer cells can use lipid molecules as fuel instead of blood glucose. This has been shown in animal tumour models by researchers at Karolinska Institutet, Sweden, in a study published in Cell Metabolism. The mechanism may explain why tumours often develop resistance to cancer drugs that inhibit the formation of blood vessels. Tumour growth […]

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Conflicting guidance on opioid prescribing can jeopardize pain management for patients with cancer

Persistent pain and recurrent episodes of pain are common for those who are living with cancer, or for those undergoing cancer treatment. When used properly, prescription opioids have long been known to help combat pain experienced by people with cancer. In the face of the worsening opioid epidemic, clinical guidelines have been published by multiple agencies to improve the way […]

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WIC participation better among vulnerable, US citizen children whose mothers are eligible for DACA

Results of a study of nearly 2,000 U.S. citizen children and their mothers add to growing evidence of the multigenerational, beneficial effects of the Deferred Action for Childhood Arrivals (DACA) immigration policy on children who are citizens, illustrating increased participation in the Special Supplemental Nutrition Program for Women, Infants and Children (WIC) among citizen children whose mothers are likely eligible […]

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Survey finds 16 percent of burn patients test positive for PTSD

A Loyola Medicine survey has found that 15.8 percent of adult burn patients screened positive for post-traumatic stress disorder (PTSD). The survey by clinical psychologist Elizabeth Simmons, PsyD, licensed clinical social worker Kelly McElligott, AM, and colleagues from Loyola Medicine’s Burn Center was presented at the annual meeting of the American Burn Association, where it was named the top poster […]

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Extended INR test intervals safe for warfarin-treated patients

(HealthDay)—For stable warfarin-treated patients, extended international normalized ratio (INR) testing can be successfully and safely implemented, according to a study published online May 15 in the Journal of Thrombosis and Haemostasis. Geoffrey D. Barnes, M.D., from the University of Michigan in Ann Arbor, and colleagues identified patients as being eligible for extended INR testing based on prior INR value stability […]

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Study finds vitamin D supplement decreases wheezing for black preterm infants

African American infants born prematurely are at higher risk for recurrent wheezing. This condition can cause the baby discomfort and is a risk factor for developing asthma later in life. There are no widely-accepted therapies to prevent prematurity-associated wheezing. In a first-of-its-kind study published in the Journal of the American Medical Association (JAMA), an University Hospitals Rainbow Babies & Children’s […]

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