Molecular chatter makes for a ‘hot tumor’

A Ludwig Cancer Research study has deciphered a complex molecular conversation between cancer and immune cells that is key to orchestrating the successful invasion of tumors by T cells that kill cancer cells. “We show that two key chemokines, CCL5 and CXCL9, are universally implicated in T cell infiltration across all solid tumors,” said George Coukos, who directs the Lausanne […]

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No evidence of legacy effect seen for intensive glucose lowering

(HealthDay)—There seems to be no evidence of a legacy effect or mortality benefit for intensive glucose control among military veterans with type 2 diabetes, according to a study published in the June 6 issue of the New England Journal of Medicine. Peter D. Reaven, M.D., from the Phoenix Veterans Affairs Health Care System, and colleagues report 15-year follow-up for intensive […]

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Genetic test for breast cancer helps women decide if preventive cancer treatment is right for them

A new study by University of Manitoba, CancerCare Manitoba and Mayo Clinic researchers has found that when women at high risk are provided with the results of genetic testing, they are more likely to take preventive medications to reduce their chances of developing breast cancer. Studies have shown that the risk of breast cancer can be reduced by half using […]

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Guidance updated for sedation in pediatric dental patients

(HealthDay)—In conjunction with the American Academy of Pediatric Dentistry, the American Academy of Pediatrics has updated its guidance for monitoring and managing pediatric dental patients during sedation; the guidelines were published online May 28 in Pediatrics. Charles J. Coté, M.D., and colleagues from the American Academy of Pediatrics and the American Academy of Pediatric Dentistry present updated guidance on delivering […]

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