Applying hand rub with 3 steps for 15 seconds as effective as WHO-recommended 6 steps for 30 seconds

A shortened 15-second application time and a simpler three-step technique for use of alcohol-based hand rub is as effective in reducing bacteria as the 30-second application and six-step technique recommended by WHO, and could improve hand hygiene compliance. The new research is being presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Amsterdam, Netherlands (13-16 […]

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New investigational antibiotic effective against drug-resistant bacteria in phase 2 trial

Results from a phase 2 randomised trial suggest that a new investigational antibiotic is as effective as the current standard-of-care antibiotic for the treatment of complicated urinary tract infections (UTIs) caused by several multidrug resistant Gram-negative bacteria. The findings, published in The Lancet Infectious Diseases, indicated that patients treated with the siderophore-based drug, cefiderocol, had a higher and more sustained […]

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Immunotherapy effective against hereditary melanoma

Individuals with an inherited form of skin cancer often have a poor prognosis. The type of immunotherapy that was awarded this year’s Nobel Prize in Physiology or Medicine is, however, particularly effective in this patient group, research from Karolinska Institutet in Sweden shows. The study is published in the Journal of Medical Genetics. Congenital mutations of the CDKN2A gene are […]

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Online diabetes prevention programs are as effective as in-person programs for weight loss

Researchers examined participation and weight loss results in an online diabetes prevention program; an in-person diabetes prevention program; and the Veterans Administration’s face-to-face standard-of-care weight management program, called MOVE! In the primary analysis, enrollees in the online diabetes prevention program saw a mean weight loss of 10.3 pounds at 6 months and 8.8 pounds at 12 months. In a secondary […]

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Effective drug delivery to heart with tannic acid

Typical methods of drug delivery to the heart require surgical procedures involving incisions in the chest wall and bones. To efficiently treat cardiovascular and related vascular diseases without surgery, a KAIST research team developed a heart-targeting drug delivery technology using tannin acid via intravenous systemic injection. This method can be applied to the development of a variety of new protein-based […]

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Spinal muscular atrophy drug may be effective if started later than previously shown

A drug shown to be effective in the treatment of babies with the rare muscle-wasting disease spinal muscular atrophy may be effective for muscle control even when treatment is started in children seven months and older, according to a study published in the August 29, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology. Previous […]

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New AI system will help us discover the most effective behaviour change strategies

Changing people’s behaviour is key to tackling the world’s health, social and environmental problems, such as obesity, sustainable living and cybersecurity. To change behaviour, though, we need to know what works, for whom, where and how. But research is generated far faster than humans can access and use it. A search on Google Scholar for “behaviour change” produced over 60,000 […]

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Stent retriever thrombectomy effective for longer window after stroke

A new study shows promising real-world outcomes for patients receiving a stent retriever thrombectomy six hours after they experience an acute ischemic stroke (AIS). The study was presented today at the Society of NeuroInterventional Surgery’s (SNIS) 15th Annual Meeting. Real-World Stent Retriever Thrombectomy for Acute Ischemic Stroke Beyond 6 Hours of Onset: Analysis of the Combined NASA and TRACK Registries […]

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Higher doses of rifampin appear more effective in fighting tuberculosis without increasing risk of adverse events

Higher daily doses of rifampin, a cornerstone of tuberculosis treatment, killed more TB bacteria in sputum cultures, and the higher doses did so without increasing the adverse effects of treatment, according to a randomized controlled trial published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine. In “Efficacy and Safety of High-Dose Rifampin in Pulmonary […]

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