familymednews.com
New results from a long-running trial to identify which new drugs or combinations of drugs are most effective in which types of breast cancer, show that two genomic tests are bringing the era of truly personalised medicine ever nearer. Professor Laura van ‘t Veer, leader of the Breast Oncology Program at the University of California San Francisco, USA, told the […]
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New research: High burden of hepatitis C among people who inject drugs highlights the urgent need for harm reduction and treatment strategies Globally, more than one in three (39%) people who have injected drugs in the last year are living with hepatitis C infection, according to new research from the National Drug and Alcohol Research Centre and the Kirby Institute […]
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For people with type 2 diabetes, switching to sulfonylurea drugs to control blood sugar levels is associated with an increased risk of complications compared with staying on the drug metformin, finds a study in The BMJ today. As such, the researchers say that continuing metformin when introducing sulfonylureas is safer than switching. Metformin is a “first-line” therapy (the first drug […]
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New methods of studying the evolution of treatment resistance in head and neck cancer are being developed by researchers at the Johns Hopkins Kimmel Cancer Center. The scientists wanted to examine how cancers acquire resistance to treatment over time and whether those changes could be modeled computationally to determine patient-specific timelines of resistance. The research was published by Genome Medicine […]
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Highly effective drugs that can cure chronic hepatitis C infection in approximately 95 percent of patients first became available in the U.S. in 2014. But both public and private insurers continue to deny coverage for these costly drugs at high rates nationwide, despite efforts to remove treatment restrictions, according to a new study published in Open Forum Infectious Diseases. The […]
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New research indicates that when pregnant women take certain rheumatoid arthritis (RA) drugs that may cause immunosuppression, their children do not have a marked excess risk of developing serious infections. The Arthritis & Rheumatology findings are potentially encouraging for women with RA who are or wish to become pregnant. In North America, infections are the leading cause of mortality in […]
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Cancer researchers at the University of Bath have measured systematically how efficient molecules are at suppressing the activity of a protein associated with prostate and other cancers. The molecules could eventually be developed into new anti-cancer drugs. The research team from the Departments of Pharmacy & Pharmacology and Chemistry are studying a protein called α-methylacyl-CoA racemase (AMACR) as a potential […]
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The treatment of cancer tumours is made complex by their microenvironment and the abnormalities of the blood vessels sustaining them. The EU-funded NeoNaNo project has developed methods to improve drug delivery to tumours and improve the efficacy of anticancer therapy. Drug delivery to tumours is difficult. The blood vessels they depend on are abnormally structured, heterogeneously distributed and relatively poorly […]
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The largest and most detailed study of the long-term impact of anticholinergic drugs, a class of drugs commonly prescribed in the United States and United Kingdom as antidepressants and incontinence medications, has found that their use is associated with increased risk of dementia, even when taken 20 years before diagnosis of cognitive impairment. An international research team from the US, […]
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New research has shown evidence that anti-epileptic drugs (AEDs) reduce bone density in children and therefore lead to an increase in the number of fractures, if used for more than a year. The study by the Murdoch Children’s Research Institute (MCRI), in conjunction with the Royal Melbourne Hospital (RMH), has prompted experts to highlight the importance of considering side effects […]
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