drug Archives - Page 5 of 6 - Family Medicine News

Study of acute myeloid leukemia patients shows protein inhibitor drug safe and effective with durable remissions

03.06.2018 Health Problems

Ivosidenib, an experimental drug that inhibits a protein often mutated in several cancers has been shown to be safe, resulting in durable remissions, in a study of acute myeloid leukemia (AML) with relapsed or refractory disease. The multi-center Phase I trial, led by researchers at The University of Texas MD Anderson Cancer Center, was designed to determine ivosidenib’s safety and […]

US approves new drug for prevention of migraines

18.05.2018 Health Problems

Migraine sufferers on Thursday got some relief from US regulators who approved the first of a new class of drugs for migraine prevention. The United States Food and Drug Administration said it endorsed Aimovig for prevention of migraine in adults, through monthly self-injections. Aimovig is the first in a new class of drugs that work by blocking the activity of […]

New study provides rationale for use of a multi-target anticancer drug in patients with malignant pleural mesothelioma

17.05.2018 Health Problems

The multi-target small molecule anticancer drug nintedanib shows promising effectiveness in stopping the growth of human malignant pleural mesothelioma, a fatal thoracic tumor, in preclinical models, according to a new study published jointly by researchers in Austria, Germany and Hungary. Malignant pleural mesothelioma is a particularly aggressive tumor that occurs in the lining that covers the lungs. It typically results […]

Osteoporosis drug may benefit heart health

11.05.2018 Health Problems

The osteoporosis drug alendronate was linked with a reduced risk of cardiovascular death, heart attack, and stroke in a Journal of Bone and Mineral Research study of patients with hip fractures. The association was seen for up to 10 years after fracture. In the study, patients newly diagnosed with hip fracture from 2005 through 2013 were followed until late 2016. […]

A new drug to help young patients with genetic obesity

09.05.2018 Health Problems

In a new study, researchers from the Institute for Experimental Pediatric Endocrinology of the Charité – Universitätsmedizin Berlin have successfully treated patients whose obesity is caused by a genetic defect. Aside from its beneficial effects on the patients, the researchers also provided insights into the fundamental signaling pathways regulating satiety of the new drug. The results of this research have […]

Mixed progress on drug resistance in A. baumannii infections in children

03.05.2018 Health Problems

In the first national study of the prevalence of antibiotic-resistant Acinetobacter baumannii infections in children across the US, researchers from Center for Disease Dynamics, Economics, & Policy (CDDEP) in Washington, DC and Rush University in Chicago, IL examined national and regional trends of antibiotic resistance in clinical specimens over a 13-year period. While there was an overall increase between 1999 […]

Virtual drug trials boost results

02.05.2018 Health Problems

Bringing a new drug to market can cost more than two billion dollars. Not to mention years of work spent developing and testing for scientists, researchers, doctors, and trial participants. By bringing trials to the virtual realm, Belinda H. Tan ’96 has found a way to cut all that in half. Her company, Science 37, is moving the entire drug […]

New lab study reveals how breast cancer drug can accelerate cancer cell growth

01.05.2018 Health Problems

The breast cancer drug lapatinib which is designed to shrink tumours can sometimes cause them to grow in the lab, according to a new study published in eLife. By understanding the molecular basis of this phenomenon, scientists hope that their findings will lead to safer treatment decision-making and drug design in the future. Lapatinib is used in combination with other […]

Evaluating drug regimens for high-risk prostate cancer

01.05.2018 Health Problems

The addition of a chemotherapy drug to adjuvant hormone therapy did not improve survival for patients with high-risk prostate cancer after surgery, according to the findings of a new clinical trial. The study, published in the Journal of Clinical Oncology, was led by Maha Hussain, MD, deputy director of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University and the Genevieve E. […]

Experimental drug extends survival in progeria

27.04.2018 Health Problems

A report from a clinical trial for a drug to treat the rapid-aging disorder progeria, published in this week’s Journal of the American Medical Association, offers hope for families with the ultra-rare genetic condition. Old Before Their Time Children with Hutchinson-Gilford Progeria Syndrome have a distinctive appearance, seemingly hurtling towards old age. After an outwardly normal infancy, weight gain slows, hair […]

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