disease Archives - Page 6 of 10 - Family Medicine News

A new model to estimate lifetime risk of atherosclerotic cardiovascular disease

24.07.2018 Health Problems

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality and also contributes to huge health care expenditures in China. Therefore, accurate and early identification of high-risk individuals is important for CVD prevention. The China-PAR (Prediction for atherosclerotic CVD (ASCVD) Risk in China) project generated equations with excellent capacity to predict lifetime risk for ASCVD by incorporating four large […]

First practice guidelines for clinical evaluation of Alzheimer’s disease

23.07.2018 Health Problems

Despite more than two decades of advances in diagnostic criteria and technology, symptoms of Alzheimer’s disease and Related Dementias (ADRD) too often go unrecognized or are misattributed, causing delays in appropriate diagnoses and care that are both harmful and costly. Contributing to the variability and inefficiency is the lack of multidisciplinary ADRD evaluation guidelines to inform U.S clinicians in primary […]

Enzyme identified as possible novel drug target for sickle cell disease, Thalassemia

22.07.2018 Health Problems

Medical researchers have identified a key signaling protein that regulates hemoglobin production in red blood cells, offering a possible target for a future innovative drug to treat sickle cell disease (SCD). Experiments in cultured human cells reveal that blocking the protein reduces the characteristic sickling that distorts the shape of red blood cells and gives the disease its name. “We […]

Novel therapy delays muscle atrophy in Lou Gehrig’s disease model

12.07.2018 Health Problems

Supplementing a single protein found in the spinal cord could help prevent symptoms of Lou Gehrig’s disease, according to a new study out of Case Western Reserve University School of Medicine. Researchers found high levels of the protein—called mitofusion 2 or Mfn2—prevented nerve degeneration, muscle atrophy, and paralysis in a mouse model of the disease. Since Mfn2 is often depleted […]

Southern diet could be deadly for people with heart disease

12.07.2018 Health Problems

People with a history of heart disease who eat a traditional Southern diet are more likely to die than those who follow a Mediterranean dietary pattern, according to new research. The large-scale study, published Thursday in the Journal of the American Heart Association, adds to the growing body of evidence on heart disease and its association with dietary patterns from […]

Synthetic surfactant could ease breathing for patients with lung disease and injury

10.07.2018 Health Problems

Human lungs are coated with a substance called surfactant which allows us to breathe easily. When lung surfactant is missing or depleted, which can happen with premature birth or lung injury, breathing becomes difficult. In a collaborative study between Lawson Health Research Institute and Stanford University, scientists have developed and tested a new synthetic surfactant that could lead to improved […]

Why the eye could be the window to brain degeneration such as Alzheimer’s disease

26.06.2018 Health Problems

Researchers from Queen’s University Belfast have shown for the first time that the eye could be a surrogate for brain degeneration like Alzheimer’s disease (AD). This research results have recently been published in the Journal of Ophthalmic Research and is the first clinical study showing a potential for peripheral retinal imaging to be used in monitoring AD and potentially other […]

New cellular pathway helps explain how inflammation leads to artery disease

23.06.2018 Health Problems

Investigators have identified a new cellular pathway that may help explain how arterial inflammation develops into atherosclerosis—deposits of cholesterol, fats and other substances that create plaque, clog arteries and promote heart attacks and stroke. The findings could lead to improved therapies for atherosclerosis, a leading cause of death worldwide. “We have known for decades that atherosclerosis is a disease of […]

Alzheimer’s breakthrough: Brain metals that may drive disease progression revealed

21.06.2018 Health Problems

Alzheimer’s disease could be better treated, thanks to a breakthrough discovery of the properties of the metals in the brain involved in the progression of the neurodegenerative condition, by an international research collaboration including the University of Warwick. Dr. Joanna Collingwood, from Warwick’s School of Engineering, was part of a research team which characterised iron species associated with the formation […]

Small vessels with big impact on cardiovascular disease

19.06.2018 Health Problems

Cardiovascular diseases are commonly associated with large vessel atherosclerosis. However, accumulating evidence demonstrates disturbances in the small arteries that control tissue perfusion. In particular, under specific conditions such as hypertension, aging, diabetes and obesity, these vessels undergo alteration in size and function, a process known as small artery remodelling. Such changes limit the capacity of these vessels to deliver oxygen […]

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